IDEAS home Printed from https://ideas.repec.org/a/nat/natcom/v9y2018i1d10.1038_s41467-018-04369-4.html
   My bibliography  Save this article

The rice blast resistance gene Ptr encodes an atypical protein required for broad-spectrum disease resistance

Author

Listed:
  • Haijun Zhao

    (USDA ARS Dale Bumpers National Rice Research Center)

  • Xueyan Wang

    (USDA ARS Dale Bumpers National Rice Research Center
    University of Arkansas Rice Research and Extension Center)

  • Yulin Jia

    (USDA ARS Dale Bumpers National Rice Research Center)

  • Bastian Minkenberg

    (The Pennsylvania State University, University Park
    University of California)

  • Matthew Wheatley

    (The Pennsylvania State University, University Park)

  • Jiangbo Fan

    (The Ohio State University)

  • Melissa H. Jia

    (USDA ARS Dale Bumpers National Rice Research Center)

  • Adam Famoso

    (Louisiana State University Agriculture Center)

  • Jeremy D. Edwards

    (USDA ARS Dale Bumpers National Rice Research Center)

  • Yeshi Wamishe

    (University of Arkansas Rice Research and Extension Center)

  • Barbara Valent

    (Kansas State University)

  • Guo-Liang Wang

    (The Ohio State University)

  • Yinong Yang

    (The Pennsylvania State University, University Park)

Abstract

Plant resistance genes typically encode proteins with nucleotide binding site-leucine rich repeat (NLR) domains. Here we show that Ptr is an atypical resistance gene encoding a protein with four Armadillo repeats. Ptr is required for broad-spectrum blast resistance mediated by the NLR R gene Pi-ta and by the associated R gene Pi-ta2. Ptr is expressed constitutively and encodes two isoforms that are mainly localized in the cytoplasm. A two base pair deletion within the Ptr coding region in the fast neutron-generated mutant line M2354 creates a truncated protein, resulting in susceptibility to M. oryzae. Targeted mutation of Ptr in a resistant cultivar using CRISPR/Cas9 leads to blast susceptibility, further confirming its resistance function. The cloning of Ptr may aid in the development of broad spectrum blast resistant rice.

Suggested Citation

  • Haijun Zhao & Xueyan Wang & Yulin Jia & Bastian Minkenberg & Matthew Wheatley & Jiangbo Fan & Melissa H. Jia & Adam Famoso & Jeremy D. Edwards & Yeshi Wamishe & Barbara Valent & Guo-Liang Wang & Yinon, 2018. "The rice blast resistance gene Ptr encodes an atypical protein required for broad-spectrum disease resistance," Nature Communications, Nature, vol. 9(1), pages 1-12, December.
    • Handle: RePEc:nat:natcom:v:9:y:2018:i:1:d:10.1038_s41467-018-04369-4
    DOI: 10.1038/s41467-018-04369-4
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/s41467-018-04369-4
    File Function: Abstract
    Download Restriction: no
    File URL: https://libkey.io/10.1038/s41467-018-04369-4?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Tran Dang Khanh & Vu Xuan Duong & Phi Cong Nguyen & Tran Dang Xuan & Nguyen Thanh Trung & Khuat Huu Trung & Dong Huy Gioi & Nguyen Huy Hoang & Hoang-Dung Tran & Do Minh Trung & Bui Thi Thu Huong, 2021. "Rice Breeding in Vietnam: Retrospects, Challenges and Prospects," Agriculture, MDPI, vol. 11(5), pages 1-21, April.
    2. Wang, Hui & Mongiano, Gabriele & Fanchini, Davide & Titone, Patrizia & Tamborini, Luigi & Bregaglio, Simone, 2021. "Varietal susceptibility overcomes climate change effects on the future trends of rice blast disease in Northern Italy," Agricultural Systems, Elsevier, vol. 193(C).

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:natcom:v:9:y:2018:i:1:d:10.1038_s41467-018-04369-4. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.