IDEAS home Printed from https://ideas.repec.org/a/nat/natcom/v9y2018i1d10.1038_s41467-017-02778-5.html
   My bibliography  Save this article

DNA-assisted swarm control in a biomolecular motor system

Author

Listed:
  • Jakia Jannat Keya

    (Hokkaido University)

  • Ryuhei Suzuki

    (Hokkaido University)

  • Arif Md. Rashedul Kabir

    (Hokkaido University)

  • Daisuke Inoue

    (Hokkaido University)

  • Hiroyuki Asanuma

    (Nagoya University)

  • Kazuki Sada

    (Hokkaido University
    Hokkaido University)

  • Henry Hess

    (Columbia University)

  • Akinori Kuzuya

    (Kansai University)

  • Akira Kakugo

    (Hokkaido University
    Hokkaido University
    Columbia University)

Abstract

In nature, swarming behavior has evolved repeatedly among motile organisms because it confers a variety of beneficial emergent properties. These include improved information gathering, protection from predators, and resource utilization. Some organisms, e.g., locusts, switch between solitary and swarm behavior in response to external stimuli. Aspects of swarming behavior have been demonstrated for motile supramolecular systems composed of biomolecular motors and cytoskeletal filaments, where cross-linkers induce large scale organization. The capabilities of such supramolecular systems may be further extended if the swarming behavior can be programmed and controlled. Here, we demonstrate that the swarming of DNA-functionalized microtubules (MTs) propelled by surface-adhered kinesin motors can be programmed and reversibly regulated by DNA signals. Emergent swarm behavior, such as translational and circular motion, can be selected by tuning the MT stiffness. Photoresponsive DNA containing azobenzene groups enables switching between solitary and swarm behavior in response to stimulation with visible or ultraviolet light.

Suggested Citation

  • Jakia Jannat Keya & Ryuhei Suzuki & Arif Md. Rashedul Kabir & Daisuke Inoue & Hiroyuki Asanuma & Kazuki Sada & Henry Hess & Akinori Kuzuya & Akira Kakugo, 2018. "DNA-assisted swarm control in a biomolecular motor system," Nature Communications, Nature, vol. 9(1), pages 1-8, December.
    • Handle: RePEc:nat:natcom:v:9:y:2018:i:1:d:10.1038_s41467-017-02778-5
    DOI: 10.1038/s41467-017-02778-5
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/s41467-017-02778-5
    File Function: Abstract
    Download Restriction: no
    File URL: https://libkey.io/10.1038/s41467-017-02778-5?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Woo Hyuk Jung & Jin Hyuk Park & Seokho Kim & Chunzhi Cui & Dong June Ahn, 2022. "Molecular doping of nucleic acids into light emitting crystals driven by multisite-intermolecular interaction," Nature Communications, Nature, vol. 13(1), pages 1-10, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:natcom:v:9:y:2018:i:1:d:10.1038_s41467-017-02778-5. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.