IDEAS home Printed from https://ideas.repec.org/a/nat/natcom/v9y2018i1d10.1038_s41467-017-02059-1.html
   My bibliography  Save this article

Designable and dynamic single-walled stiff nanotubes assembled from sequence-defined peptoids

Author

Listed:
  • Haibao Jin

    (Physical Sciences Division, Pacific Northwest National Laboratory)

  • Yan-Huai Ding

    (Physical Sciences Division, Pacific Northwest National Laboratory
    Institute of Rheological Mechanics, Xiangtan University)

  • Mingming Wang

    (Physical Sciences Division, Pacific Northwest National Laboratory)

  • Yang Song

    (Physical Sciences Division, Pacific Northwest National Laboratory
    School of Mechanical and Materials Engineering, Washington State University)

  • Zhihao Liao

    (Physical Sciences Division, Pacific Northwest National Laboratory
    Center for Biomaterials and Biopathways, Department of Chemistry, Zhejiang University)

  • Christina J. Newcomb

    (Physical Sciences Division, Pacific Northwest National Laboratory)

  • Xuepeng Wu

    (Physical Sciences Division, Pacific Northwest National Laboratory
    School of Petroleum Engineering, State Key Laboratory of Heavy Oil Processing, China University of Petroleum (East China))

  • Xian-Qiong Tang

    (Institute of Rheological Mechanics, Xiangtan University)

  • Zheng Li

    (Institute of Rheological Mechanics, Xiangtan University)

  • Yuehe Lin

    (School of Mechanical and Materials Engineering, Washington State University)

  • Feng Yan

    (Physical Sciences Division, Pacific Northwest National Laboratory
    College of Chemistry and Chemical Engineering, Linyi University)

  • Tengyue Jian

    (Physical Sciences Division, Pacific Northwest National Laboratory)

  • Peng Mu

    (Physical Sciences Division, Pacific Northwest National Laboratory
    State University of New York)

  • Chun-Long Chen

    (Physical Sciences Division, Pacific Northwest National Laboratory)

Abstract

Despite recent advances in the assembly of organic nanotubes, conferral of sequence-defined engineering and dynamic response characteristics to the tubules remains a challenge. Here we report a new family of highly designable and dynamic nanotubes assembled from sequence-defined peptoids through a unique “rolling-up and closure of nanosheet” mechanism. During the assembly process, amorphous spherical particles of amphiphilic peptoid oligomers crystallize to form well-defined nanosheets before folding to form single-walled nanotubes. These nanotubes undergo a pH-triggered, reversible contraction–expansion motion. By varying the number of hydrophobic residues of peptoids, we demonstrate tuning of nanotube wall thickness, diameter, and mechanical properties. Atomic force microscopy-based mechanical measurements show peptoid nanotubes are highly stiff (Young’s Modulus ~13–17 GPa). We further demonstrate the precise incorporation of functional groups within nanotubes and their applications in water decontamination and cellular adhesion and uptake. These nanotubes provide a robust platform for developing biomimetic materials tailored to specific applications.

Suggested Citation

  • Haibao Jin & Yan-Huai Ding & Mingming Wang & Yang Song & Zhihao Liao & Christina J. Newcomb & Xuepeng Wu & Xian-Qiong Tang & Zheng Li & Yuehe Lin & Feng Yan & Tengyue Jian & Peng Mu & Chun-Long Chen, 2018. "Designable and dynamic single-walled stiff nanotubes assembled from sequence-defined peptoids," Nature Communications, Nature, vol. 9(1), pages 1-11, December.
    • Handle: RePEc:nat:natcom:v:9:y:2018:i:1:d:10.1038_s41467-017-02059-1
    DOI: 10.1038/s41467-017-02059-1
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/s41467-017-02059-1
    File Function: Abstract
    Download Restriction: no
    File URL: https://libkey.io/10.1038/s41467-017-02059-1?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Tengyue Jian & Yicheng Zhou & Peipei Wang & Wenchao Yang & Peng Mu & Xin Zhang & Xiao Zhang & Chun-Long Chen, 2022. "Highly stable and tunable peptoid/hemin enzymatic mimetics with natural peroxidase-like activities," Nature Communications, Nature, vol. 13(1), pages 1-13, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:natcom:v:9:y:2018:i:1:d:10.1038_s41467-017-02059-1. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.