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Solution nuclear magnetic resonance spectroscopy on a nanostructured diamond chip

Author

Listed:
  • P. Kehayias

    (Harvard University
    University of New Mexico)

  • A. Jarmola

    (ODMR Technologies Inc.
    University of California-Berkeley)

  • N. Mosavian

    (University of New Mexico)

  • I. Fescenko

    (University of New Mexico)

  • F. M. Benito

    (University of New Mexico)

  • A. Laraoui

    (University of New Mexico)

  • J. Smits

    (University of New Mexico)

  • L. Bougas

    (Johannes Gutenberg Universität Mainz)

  • D. Budker

    (ODMR Technologies Inc.
    University of California-Berkeley
    Helmholtz Institut Mainz)

  • A. Neumann

    (University of New Mexico)

  • S. R. J. Brueck

    (University of New Mexico)

  • V. M. Acosta

    (University of New Mexico)

Abstract

Sensors using nitrogen-vacancy centers in diamond are a promising tool for small-volume nuclear magnetic resonance (NMR) spectroscopy, but the limited sensitivity remains a challenge. Here we show nearly two orders of magnitude improvement in concentration sensitivity over previous nitrogen-vacancy and picoliter NMR studies. We demonstrate NMR spectroscopy of picoliter-volume solutions using a nanostructured diamond chip with dense, high-aspect-ratio nanogratings, enhancing the surface area by 15 times. The nanograting sidewalls are doped with nitrogen-vacancies located a few nanometers from the diamond surface to detect the NMR spectrum of roughly 1 pl of fluid lying within adjacent nanograting grooves. We perform 1H and 19F nuclear magnetic resonance spectroscopy at room temperature in magnetic fields below 50 mT. Using a solution of CsF in glycerol, we determine that 4 ± 2 × 1012 19F spins in a 1 pl volume can be detected with a signal-to-noise ratio of 3 in 1 s of integration.

Suggested Citation

  • P. Kehayias & A. Jarmola & N. Mosavian & I. Fescenko & F. M. Benito & A. Laraoui & J. Smits & L. Bougas & D. Budker & A. Neumann & S. R. J. Brueck & V. M. Acosta, 2017. "Solution nuclear magnetic resonance spectroscopy on a nanostructured diamond chip," Nature Communications, Nature, vol. 8(1), pages 1-8, December.
    • Handle: RePEc:nat:natcom:v:8:y:2017:i:1:d:10.1038_s41467-017-00266-4
    DOI: 10.1038/s41467-017-00266-4
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    Cited by:

    1. M. Victoria Gomez & Sander Baas & Aldrik H. Velders, 2023. "Multinuclear 1D and 2D NMR with 19F-Photo-CIDNP hyperpolarization in a microfluidic chip with untuned microcoil," Nature Communications, Nature, vol. 14(1), pages 1-14, December.

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