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Arabidopsis proteins with a transposon-related domain act in gene silencing

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  • Yoko Ikeda

    (Université Clermont Auvergne, CNRS, Inserm, GReD
    Institute of Plant Science and Resources, Okayama University)

  • Thierry Pélissier

    (Université Clermont Auvergne, CNRS, Inserm, GReD)

  • Pierre Bourguet

    (Université Clermont Auvergne, CNRS, Inserm, GReD)

  • Claude Becker

    (Max Planck Institute for Developmental Biology)

  • Marie-Noëlle Pouch-Pélissier

    (Université Clermont Auvergne, CNRS, Inserm, GReD)

  • Romain Pogorelcnik

    (Université Clermont Auvergne, CNRS, Inserm, GReD)

  • Magdalena Weingartner

    (Molekulare Pflanzenphysiologie, Biozentrum Klein Flottbek, Universität Hamburg)

  • Detlef Weigel

    (Max Planck Institute for Developmental Biology)

  • Jean-Marc Deragon

    (Laboratoire Génome et Développement des Plantes (LGDP), CNRS, UMR5096, Université de Perpignan Via Domitia)

  • Olivier Mathieu

    (Université Clermont Auvergne, CNRS, Inserm, GReD)

Abstract

Transposable elements (TEs) are prevalent in most eukaryotes, and host genomes have devised silencing strategies to rein in TE activity. One of these, transcriptional silencing, is generally associated with DNA methylation and short interfering RNAs. Here we show that the Arabidopsis genes MAIL1 and MAIN define an alternative silencing pathway independent of DNA methylation and short interfering RNAs. Mutants for MAIL1 or MAIN exhibit release of silencing and appear to show impaired condensation of pericentromeric heterochromatin. Phylogenetic analysis suggests not only that MAIL1 and MAIN encode a retrotransposon-related plant mobile domain, but also that host plant mobile domains were captured by DNA transposons during plant evolution. Our results reveal a role for Arabidopsis proteins with a transposon-related domain in gene silencing.

Suggested Citation

  • Yoko Ikeda & Thierry Pélissier & Pierre Bourguet & Claude Becker & Marie-Noëlle Pouch-Pélissier & Romain Pogorelcnik & Magdalena Weingartner & Detlef Weigel & Jean-Marc Deragon & Olivier Mathieu, 2017. "Arabidopsis proteins with a transposon-related domain act in gene silencing," Nature Communications, Nature, vol. 8(1), pages 1-10, August.
    • Handle: RePEc:nat:natcom:v:8:y:2017:i:1:d:10.1038_ncomms15122
    DOI: 10.1038/ncomms15122
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