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GABAergic anxiolytic drug in water increases migration behaviour in salmon

Author

Listed:
  • Gustav Hellström

    (Umeå University)

  • Jonatan Klaminder

    (Umeå University)

  • Fia Finn

    (Umeå University)

  • Lo Persson

    (Fish and Environmental Studies, Swedish University of Agricultural Sciences)

  • Anders Alanärä

    (Fish and Environmental Studies, Swedish University of Agricultural Sciences)

  • Micael Jonsson

    (Umeå University)

  • Jerker Fick

    (Umeå University)

  • Tomas Brodin

    (Umeå University)

Abstract

Migration is an important life-history event in a wide range of taxa, yet many migrations are influenced by anthropogenic change. Although migration dynamics are extensively studied, the potential effects of environmental contaminants on migratory physiology are poorly understood. In this study we show that an anxiolytic drug in water can promote downward migratory behaviour of Atlantic salmon (Salmo salar) in both laboratory setting and in a natural river tributary. Exposing salmon smolt to a dilute concentration of a GABAA receptor agonist (oxazepam) increased migration intensity compared with untreated smolt. These results implicate that salmon migration may be affected by human-induced changes in water chemical properties, such as acidification and pharmaceutical residues in wastewater effluent, via alterations in the GABAA receptor function.

Suggested Citation

  • Gustav Hellström & Jonatan Klaminder & Fia Finn & Lo Persson & Anders Alanärä & Micael Jonsson & Jerker Fick & Tomas Brodin, 2016. "GABAergic anxiolytic drug in water increases migration behaviour in salmon," Nature Communications, Nature, vol. 7(1), pages 1-7, December.
    • Handle: RePEc:nat:natcom:v:7:y:2016:i:1:d:10.1038_ncomms13460
    DOI: 10.1038/ncomms13460
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