IDEAS home Printed from https://ideas.repec.org/a/nat/natcom/v7y2016i1d10.1038_ncomms10678.html
   My bibliography  Save this article

Functional dissociation in sweet taste receptor neurons between and within taste organs of Drosophila

Author

Listed:
  • Vladimiros Thoma

    (Graduate School of Life Sciences, Tohoku University
    Max-Planck Institut für Neurobiologie)

  • Stephan Knapek

    (Max-Planck Institut für Neurobiologie)

  • Shogo Arai

    (Graduate School of Information Sciences, Tohoku University)

  • Marion Hartl

    (Max-Planck Institut für Neurobiologie
    Present address: Gut Signalling and Metabolism Group, MRC Clinical Sciences Centre, Imperial College London, Du Cane Road, London W12 0NN, UK.)

  • Hiroshi Kohsaka

    (Graduate School of Frontier Sciences, The University of Tokyo)

  • Pudith Sirigrivatanawong

    (Graduate School of Information Sciences, Tohoku University)

  • Ayako Abe

    (Graduate School of Life Sciences, Tohoku University)

  • Koichi Hashimoto

    (Graduate School of Information Sciences, Tohoku University)

  • Hiromu Tanimoto

    (Graduate School of Life Sciences, Tohoku University
    Max-Planck Institut für Neurobiologie)

Abstract

Finding food sources is essential for survival. Insects detect nutrients with external taste receptor neurons. Drosophila possesses multiple taste organs that are distributed throughout its body. However, the role of different taste organs in feeding remains poorly understood. By blocking subsets of sweet taste receptor neurons, we show that receptor neurons in the legs are required for immediate sugar choice. Furthermore, we identify two anatomically distinct classes of sweet taste receptor neurons in the leg. The axonal projections of one class terminate in the thoracic ganglia, whereas the other projects directly to the brain. These two classes are functionally distinct: the brain-projecting neurons are involved in feeding initiation, whereas the thoracic ganglia-projecting neurons play a role in sugar-dependent suppression of locomotion. Distinct receptor neurons for the same taste quality may coordinate early appetitive responses, taking advantage of the legs as the first appendages to contact food.

Suggested Citation

  • Vladimiros Thoma & Stephan Knapek & Shogo Arai & Marion Hartl & Hiroshi Kohsaka & Pudith Sirigrivatanawong & Ayako Abe & Koichi Hashimoto & Hiromu Tanimoto, 2016. "Functional dissociation in sweet taste receptor neurons between and within taste organs of Drosophila," Nature Communications, Nature, vol. 7(1), pages 1-11, April.
  • Handle: RePEc:nat:natcom:v:7:y:2016:i:1:d:10.1038_ncomms10678
    DOI: 10.1038/ncomms10678
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/ncomms10678
    File Function: Abstract
    Download Restriction: no

    File URL: https://libkey.io/10.1038/ncomms10678?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Stanislav Ott & Sangyu Xu & Nicole Lee & Ivan Hong & Jonathan Anns & Danesha Devini Suresh & Zhiyi Zhang & Xianyuan Zhang & Raihanah Harion & Weiying Ye & Vaishnavi Chandramouli & Suresh Jesuthasan & , 2024. "Kalium channelrhodopsins effectively inhibit neurons," Nature Communications, Nature, vol. 15(1), pages 1-21, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:natcom:v:7:y:2016:i:1:d:10.1038_ncomms10678. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.