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A phospholipid uptake system in the model plant Arabidopsis thaliana

Author

Listed:
  • Lisbeth R. Poulsen

    (Centre for Membrane Pumps in Cells and Disease—PUMPKIN, University of Copenhagen)

  • Rosa L. López-Marqués

    (Centre for Membrane Pumps in Cells and Disease—PUMPKIN, University of Copenhagen)

  • Pai R. Pedas

    (Centre for Membrane Pumps in Cells and Disease—PUMPKIN, University of Copenhagen)

  • Stephen C. McDowell

    (University of Nevada)

  • Elizabeth Brown

    (University of Nevada)

  • Reinhard Kunze

    (Dahlem Centre of Plant Sciences (DCPS), Freie Universität Berlin)

  • Jeffrey F. Harper

    (University of Nevada)

  • Thomas G. Pomorski

    (Centre for Membrane Pumps in Cells and Disease—PUMPKIN, University of Copenhagen)

  • Michael Palmgren

    (Centre for Membrane Pumps in Cells and Disease—PUMPKIN, University of Copenhagen)

Abstract

Plants use solar energy to produce lipids directly from inorganic elements and are not thought to require molecular systems for lipid uptake from the environment. Here we show that Arabidopsis thaliana Aminophospholipid ATPase10 (ALA10) is a P4-type ATPase flippase that internalizes exogenous phospholipids across the plasma membrane, after which they are rapidly metabolized. ALA10 expression and phospholipid uptake are high in the epidermal cells of the root tip and in guard cells, the latter of which regulate the size of stomatal apertures to modulate gas exchange. ALA10-knockout mutants exhibit reduced phospholipid uptake at the root tips and guard cells and are affected in growth and transpiration. The presence of a phospholipid uptake system in plants is surprising. Our results suggest that one possible physiological role of this system is to internalize lysophosphatidylcholine, a signalling lipid involved in root development and stomatal control.

Suggested Citation

  • Lisbeth R. Poulsen & Rosa L. López-Marqués & Pai R. Pedas & Stephen C. McDowell & Elizabeth Brown & Reinhard Kunze & Jeffrey F. Harper & Thomas G. Pomorski & Michael Palmgren, 2015. "A phospholipid uptake system in the model plant Arabidopsis thaliana," Nature Communications, Nature, vol. 6(1), pages 1-14, November.
    • Handle: RePEc:nat:natcom:v:6:y:2015:i:1:d:10.1038_ncomms8649
    DOI: 10.1038/ncomms8649
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