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Unravelling the hidden ancestry of American admixed populations

Author

Listed:
  • Francesco Montinaro

    (Institute of Legal Medicine, Catholic University
    University of Oxford)

  • George B.J. Busby

    (University of Oxford
    Wellcome Trust Center for Human Genetics)

  • Vincenzo L. Pascali

    (Institute of Legal Medicine, Catholic University)

  • Simon Myers

    (Wellcome Trust Center for Human Genetics
    University of Oxford)

  • Garrett Hellenthal

    (UCL Genetics Institute, University College London)

  • Cristian Capelli

    (University of Oxford)

Abstract

The movement of people into the Americas has brought different populations into contact, and contemporary American genomes are the product of a range of complex admixture events. Here we apply a haplotype-based ancestry identification approach to a large set of genome-wide SNP data from a variety of American, European and African populations to determine the contributions of different ancestral populations to the Americas. Our results provide a fine-scale characterization of the source populations, identify a series of novel, previously unreported contributions from Africa and Europe and highlight geohistorical structure in the ancestry of American admixed populations.

Suggested Citation

  • Francesco Montinaro & George B.J. Busby & Vincenzo L. Pascali & Simon Myers & Garrett Hellenthal & Cristian Capelli, 2015. "Unravelling the hidden ancestry of American admixed populations," Nature Communications, Nature, vol. 6(1), pages 1-7, May.
    • Handle: RePEc:nat:natcom:v:6:y:2015:i:1:d:10.1038_ncomms7596
    DOI: 10.1038/ncomms7596
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    Cited by:

    1. Julian R Homburger & Andrés Moreno-Estrada & Christopher R Gignoux & Dominic Nelson & Elena Sanchez & Patricia Ortiz-Tello & Bernardo A Pons-Estel & Eduardo Acevedo-Vasquez & Pedro Miranda & Carl D La, 2015. "Genomic Insights into the Ancestry and Demographic History of South America," PLOS Genetics, Public Library of Science, vol. 11(12), pages 1-26, December.

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