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CHOLINE TRANSPORTER-LIKE1 is required for sieve plate development to mediate long-distance cell-to-cell communication

Author

Listed:
  • Jan Dettmer

    (University of Erlangen-Nuremberg)

  • Robertas Ursache

    (Institute of Biotechnology, University of Helsinki)

  • Ana Campilho

    (Institute for Molecular and Cell Biology (IBMC), University of Porto)

  • Shunsuke Miyashima

    (Institute of Biotechnology, University of Helsinki)

  • Ilya Belevich

    (Institute of Biotechnology, University of Helsinki)

  • Seana O’Regan

    (Neurophotonics Laboratory, CNRS/Université Paris Descartes, 45, rue des Saints-Pères)

  • Daniel Leroy Mullendore

    (School of Biological Sciences, Washington State University)

  • Shri Ram Yadav

    (Institute of Biotechnology, University of Helsinki)

  • Christa Lanz

    (Max Planck Institute for Developmental Biology)

  • Luca Beverina

    (University of Milano-Bicocca, Via R. Cozzi 55)

  • Antonio Papagni

    (University of Milano-Bicocca, Via R. Cozzi 55)

  • Korbinian Schneeberger

    (Max Planck Institute for Plant Breeding Research)

  • Detlef Weigel

    (Max Planck Institute for Developmental Biology)

  • York-Dieter Stierhof

    (ZMBP, Mikroskopie, Universität Tübingen, Auf der Morgenstelle 5)

  • Thomas Moritz

    (Umeå Plant Science Center, Swedish University of Agricultural Sciences)

  • Michael Knoblauch

    (School of Biological Sciences, Washington State University)

  • Eija Jokitalo

    (Institute of Biotechnology, University of Helsinki)

  • Ykä Helariutta

    (Institute of Biotechnology, University of Helsinki)

Abstract

Phloem, a plant tissue responsible for long-distance molecular transport, harbours specific junctions, sieve areas, between the conducting cells. To date, little is known about the molecular framework related to the biogenesis of these sieve areas. Here we identify mutations at the CHER1/AtCTL1 locus of Arabidopsis thaliana. The mutations cause several phenotypic abnormalities, including reduced pore density and altered pore structure in the sieve areas associated with impaired phloem function. CHER1 encodes a member of a poorly characterized choline transporter-like protein family in plants and animals. We show that CHER1 facilitates choline transport, localizes to the trans-Golgi network, and during cytokinesis is associated with the phragmoplast. Consistent with its function in the elaboration of the sieve areas, CHER1 has a sustained, polar localization in the forming sieve plates. Our results indicate that the regulation of choline levels is crucial for phloem development and conductivity in plants.

Suggested Citation

  • Jan Dettmer & Robertas Ursache & Ana Campilho & Shunsuke Miyashima & Ilya Belevich & Seana O’Regan & Daniel Leroy Mullendore & Shri Ram Yadav & Christa Lanz & Luca Beverina & Antonio Papagni & Korbini, 2014. "CHOLINE TRANSPORTER-LIKE1 is required for sieve plate development to mediate long-distance cell-to-cell communication," Nature Communications, Nature, vol. 5(1), pages 1-11, September.
    • Handle: RePEc:nat:natcom:v:5:y:2014:i:1:d:10.1038_ncomms5276
    DOI: 10.1038/ncomms5276
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    Cited by:

    1. Ilya Belevich & Merja Joensuu & Darshan Kumar & Helena Vihinen & Eija Jokitalo, 2016. "Microscopy Image Browser: A Platform for Segmentation and Analysis of Multidimensional Datasets," PLOS Biology, Public Library of Science, vol. 14(1), pages 1-13, January.

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