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TERRA transcripts are bound by a complex array of RNA-binding proteins

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Listed:
  • Isabel López de Silanes

    (Telomeres and Telomerase Group, Molecular Oncology Program, Spanish National Cancer Research Centre (CNIO))

  • Martina Stagno d'Alcontres

    (Telomeres and Telomerase Group, Molecular Oncology Program, Spanish National Cancer Research Centre (CNIO))

  • Maria A Blasco

    (Telomeres and Telomerase Group, Molecular Oncology Program, Spanish National Cancer Research Centre (CNIO))

Abstract

Recent work has revealed that the TTAGGG DNA repeats of telomeres are transcribed to form 'TERRA'. In this study, a set of RNA-binding proteins are shown to bind TERRA transcripts, altering the location of these transcripts at telomeres and regulating telomere abundance and length.

Suggested Citation

  • Isabel López de Silanes & Martina Stagno d'Alcontres & Maria A Blasco, 2010. "TERRA transcripts are bound by a complex array of RNA-binding proteins," Nature Communications, Nature, vol. 1(1), pages 1-10, December.
    • Handle: RePEc:nat:natcom:v:1:y:2010:i:1:d:10.1038_ncomms1032
    DOI: 10.1038/ncomms1032
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    Cited by:

    1. Johanna Luige & Alexandros Armaos & Gian Gaetano Tartaglia & Ulf Andersson Vang Ørom, 2024. "Predicting nuclear G-quadruplex RNA-binding proteins with roles in transcription and phase separation," Nature Communications, Nature, vol. 15(1), pages 1-13, December.

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