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Estimating the burden of severe malarial anaemia and access to hospital care in East Africa

Author

Listed:
  • Peter Winskill

    (Imperial College)

  • Aggrey Dhabangi

    (Makerere University College of Health Sciences)

  • Titus K. Kwambai

    (Centers for Disease Control and Prevention)

  • Amani Thomas Mori

    (University of Bergen
    Muhimbili University of Health and Allied Sciences, P.O. Box)

  • Andria Mousa

    (London School of Hygiene and Tropical Medicine)

  • Lucy C. Okell

    (Imperial College)

Abstract

Severe malarial anaemia can be fatal if not promptly treated. Hospital studies may under-represent the true burden because cases often occur in settings with poor access to healthcare. We estimate the relationship of community prevalence of malaria infection and severe malarial anaemia with the incidence of severe malarial anaemia cases in hospital, using survey data from 21 countries and hospital data from Kenya, Tanzania and Uganda. The estimated percentage of severe malarial anaemia cases that were hospitalised is low and consistent for Kenya (21% (95% CrI: 7%, 47%)), Tanzania (18% (95% CrI: 5%, 52%)) and Uganda (23% (95% CrI: 9%, 48%)). The majority of severe malarial anaemia cases remain in the community, with the consequent public health burden being contingent upon the severity of these cases. Alongside health system strengthening, research to better understand the spectrum of disease associated with severe malarial anaemia cases in the community is a priority.

Suggested Citation

  • Peter Winskill & Aggrey Dhabangi & Titus K. Kwambai & Amani Thomas Mori & Andria Mousa & Lucy C. Okell, 2023. "Estimating the burden of severe malarial anaemia and access to hospital care in East Africa," Nature Communications, Nature, vol. 14(1), pages 1-7, December.
    • Handle: RePEc:nat:natcom:v:14:y:2023:i:1:d:10.1038_s41467-023-41275-w
    DOI: 10.1038/s41467-023-41275-w
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    References listed on IDEAS

    as
    1. Lindsey Wu & Lotus L. van den Hoogen & Hannah Slater & Patrick G. T. Walker & Azra C. Ghani & Chris J. Drakeley & Lucy C. Okell, 2015. "Comparison of diagnostics for the detection of asymptomatic Plasmodium falciparum infections to inform control and elimination strategies," Nature, Nature, vol. 528(7580), pages 86-93, December.
    2. D'Ambruoso, Lucia & Byass, Peter & Qomariyah, Siti Nurul & Ouédraogo, Moctar, 2010. "A lost cause? Extending verbal autopsy to investigate biomedical and socio-cultural causes of maternal death in Burkina Faso and Indonesia," Social Science & Medicine, Elsevier, vol. 71(10), pages 1728-1738, November.
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