Author
Listed:
- Susana Matamouros
(IBG-1: Biotechnology, Forschungszentrum Jülich)
- Thomas Gensch
(IBI-1: Molecular and Cellular Physiology, Forschungszentrum Jülich)
- Martin Cerff
(IBG-1: Biotechnology, Forschungszentrum Jülich)
- Christian C. Sachs
(IBG-1: Biotechnology, Forschungszentrum Jülich)
- Iman Abdollahzadeh
(IBI-1: Molecular and Cellular Physiology, Forschungszentrum Jülich)
- Johnny Hendriks
(IBI-1: Molecular and Cellular Physiology, Forschungszentrum Jülich)
- Lucas Horst
(IBG-1: Biotechnology, Forschungszentrum Jülich)
- Niklas Tenhaef
(IBG-1: Biotechnology, Forschungszentrum Jülich)
- Julia Tenhaef
(IBG-1: Biotechnology, Forschungszentrum Jülich)
- Stephan Noack
(IBG-1: Biotechnology, Forschungszentrum Jülich)
- Michaela Graf
(University of Stuttgart)
- Ralf Takors
(University of Stuttgart)
- Katharina Nöh
(IBG-1: Biotechnology, Forschungszentrum Jülich)
- Michael Bott
(IBG-1: Biotechnology, Forschungszentrum Jülich)
Abstract
Bacterial growth rate (µ) depends on the protein synthesis capacity of the cell and thus on the number of active ribosomes and their translation elongation rate. The relationship between these fundamental growth parameters have only been described for few bacterial species, in particular Escherichia coli. Here, we analyse the growth-rate dependency of ribosome abundance and translation elongation rate for Corynebacterium glutamicum, a gram-positive model species differing from E. coli by a lower growth temperature optimum and a lower maximal growth rate. We show that, unlike in E. coli, there is little change in ribosome abundance for µ
Suggested Citation
Susana Matamouros & Thomas Gensch & Martin Cerff & Christian C. Sachs & Iman Abdollahzadeh & Johnny Hendriks & Lucas Horst & Niklas Tenhaef & Julia Tenhaef & Stephan Noack & Michaela Graf & Ralf Takor, 2023.
"Growth-rate dependency of ribosome abundance and translation elongation rate in Corynebacterium glutamicum differs from that in Escherichia coli,"
Nature Communications, Nature, vol. 14(1), pages 1-14, December.
Handle:
RePEc:nat:natcom:v:14:y:2023:i:1:d:10.1038_s41467-023-41176-y
DOI: 10.1038/s41467-023-41176-y
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