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Evaluation of mortality attributable to SARS-CoV-2 vaccine administration using national level data from Qatar

Author

Listed:
  • Adeel A. Butt

    (Hamad Medical Corporation
    Weill Cornell Medicine
    Weill Cornell Medicine
    Weill Cornell Medicine)

  • Mylai D. Guerrero

    (Hamad Medical Corporation)

  • Elenor B. Canlas

    (Hamad Medical Corporation)

  • Husni Al-Dwairi

    (Hamad Medical Corporation)

  • Abeir Bakhiet Mohammed Ali Alimam

    (Hamad Medical Corporation)

  • Abdur Rehman Mohamad

    (Hamad Medical Corporation)

  • Mohammed Thamer Ali

    (Hamad Medical Corporation)

  • Nidal Ahmad Asaad

    (Hamad Medical Corporation)

  • Ali Ahmed Sheikh Saleh Alkeldi

    (Hamad Medical Corporation)

  • Mohammad Fawaz Saber Mohammad

    (Hamad Medical Corporation)

  • Anil G. Thomas

    (Hamad Medical Corporation)

  • Abdullatif Al-Khal

    (Hamad Medical Corporation)

  • Muna Al-Maslamani

    (Hamad Medical Corporation)

  • Abdul-Badi Abou-Samra

    (Hamad Medical Corporation
    Weill Cornell Medicine)

Abstract

Accurate determination of mortality attributable to SARS-CoV-2 vaccination is critical in allaying concerns about their safety. We reviewed every death in Qatar that occurred within 30 days of any SARS-CoV-2 vaccine administration between January 1, 2021 and June 12, 2022. Probability of association with SARS-CoV-2 vaccination was determined by four independent trained reviewers using a modified WHO algorithm. Among 6,928,359 doses administered, 138 deaths occurred within 30 days of vaccination; eight had a high probability (1.15/1,000,000 doses), 15 had intermediate probability (2.38/1,000,000 doses), and 112 had low probability or no association with vaccination. The death rate among those with high probability of relationship to SARS-CoV-2 vaccination was 0.34/100,000 unique vaccine recipients, while death rate among those with either high or intermediate probability of relationship to SARS-CoV-2 vaccination was 0.98/100,000 unique vaccine recipients. In conclusion, deaths attributable to SARS-CoV-2 vaccination are extremely rare and lower than the overall crude mortality rate in Qatar.

Suggested Citation

  • Adeel A. Butt & Mylai D. Guerrero & Elenor B. Canlas & Husni Al-Dwairi & Abeir Bakhiet Mohammed Ali Alimam & Abdur Rehman Mohamad & Mohammed Thamer Ali & Nidal Ahmad Asaad & Ali Ahmed Sheikh Saleh Alk, 2023. "Evaluation of mortality attributable to SARS-CoV-2 vaccine administration using national level data from Qatar," Nature Communications, Nature, vol. 14(1), pages 1-5, December.
    • Handle: RePEc:nat:natcom:v:14:y:2023:i:1:d:10.1038_s41467-022-35653-z
    DOI: 10.1038/s41467-022-35653-z
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