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Population fluctuations and synanthropy explain transmission risk in rodent-borne zoonoses

Author

Listed:
  • Frauke Ecke

    (Swedish University of Agricultural Sciences
    University of Helsinki)

  • Barbara A. Han

    (Cary Institute of Ecosystem Studies, Millbrook)

  • Birger Hörnfeldt

    (Swedish University of Agricultural Sciences)

  • Hussein Khalil

    (Swedish University of Agricultural Sciences)

  • Magnus Magnusson

    (Swedish University of Agricultural Sciences
    Swedish Forest Agency)

  • Navinder J. Singh

    (Swedish University of Agricultural Sciences)

  • Richard S. Ostfeld

    (Cary Institute of Ecosystem Studies, Millbrook)

Abstract

Population fluctuations are widespread across the animal kingdom, especially in the order Rodentia, which includes many globally important reservoir species for zoonotic pathogens. The implications of these fluctuations for zoonotic spillover remain poorly understood. Here, we report a global empirical analysis of data describing the linkages between habitat use, population fluctuations and zoonotic reservoir status in rodents. Our quantitative synthesis is based on data collated from papers and databases. We show that the magnitude of population fluctuations combined with species’ synanthropy and degree of human exploitation together distinguish most rodent reservoirs at a global scale, a result that was consistent across all pathogen types and pathogen transmission modes. Our spatial analyses identified hotspots of high transmission risk, including regions where reservoir species dominate the rodent community. Beyond rodents, these generalities inform our understanding of how natural and anthropogenic factors interact to increase the risk of zoonotic spillover in a rapidly changing world.

Suggested Citation

  • Frauke Ecke & Barbara A. Han & Birger Hörnfeldt & Hussein Khalil & Magnus Magnusson & Navinder J. Singh & Richard S. Ostfeld, 2022. "Population fluctuations and synanthropy explain transmission risk in rodent-borne zoonoses," Nature Communications, Nature, vol. 13(1), pages 1-10, December.
    • Handle: RePEc:nat:natcom:v:13:y:2022:i:1:d:10.1038_s41467-022-35273-7
    DOI: 10.1038/s41467-022-35273-7
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    References listed on IDEAS

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    1. Kate E. Jones & Nikkita G. Patel & Marc A. Levy & Adam Storeygard & Deborah Balk & John L. Gittleman & Peter Daszak, 2008. "Global trends in emerging infectious diseases," Nature, Nature, vol. 451(7181), pages 990-993, February.
    2. Kevin J. Olival & Parviez R. Hosseini & Carlos Zambrana-Torrelio & Noam Ross & Tiffany L. Bogich & Peter Daszak, 2017. "Erratum: Host and viral traits predict zoonotic spillover from mammals," Nature, Nature, vol. 548(7669), pages 612-612, August.
    3. Rory Gibb & David W. Redding & Kai Qing Chin & Christl A. Donnelly & Tim M. Blackburn & Tim Newbold & Kate E. Jones, 2020. "Zoonotic host diversity increases in human-dominated ecosystems," Nature, Nature, vol. 584(7821), pages 398-402, August.
    4. Kevin J. Olival & Parviez R. Hosseini & Carlos Zambrana-Torrelio & Noam Ross & Tiffany L. Bogich & Peter Daszak, 2017. "Host and viral traits predict zoonotic spillover from mammals," Nature, Nature, vol. 546(7660), pages 646-650, June.
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