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Paving the way to improve therapy for Myeloproliferative Neoplasms

Author

Listed:
  • Megan Bywater

    (QIMR Berghofer MRI
    University of Queensland)

  • Steven W. Lane

    (QIMR Berghofer MRI
    University of Queensland
    Royal Brisbane and Women’s Hospital)

Abstract

Long-acting IFNα induces durable molecular responses in myeloproliferative neoplasms. Emerging studies, including Saleiro et al. recently published in Nature Communications, have identified promising candidates that may synergise with IFNα by targeting stem cell function or feedback loops that mediate treatment resistance.

Suggested Citation

  • Megan Bywater & Steven W. Lane, 2022. "Paving the way to improve therapy for Myeloproliferative Neoplasms," Nature Communications, Nature, vol. 13(1), pages 1-3, December.
    • Handle: RePEc:nat:natcom:v:13:y:2022:i:1:d:10.1038_s41467-022-32694-2
    DOI: 10.1038/s41467-022-32694-2
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    References listed on IDEAS

    as
    1. Diana Saleiro & Jeremy Q. Wen & Ewa M. Kosciuczuk & Frank Eckerdt & Elspeth M. Beauchamp & Chidera V. Oku & Gavin T. Blyth & Mariafausta Fischietti & Liliana Ilut & Marco Colamonici & William Palivos , 2022. "Discovery of a signaling feedback circuit that defines interferon responses in myeloproliferative neoplasms," Nature Communications, Nature, vol. 13(1), pages 1-19, December.
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