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T follicular helper and B cell crosstalk in tertiary lymphoid structures and cancer immunotherapy

Author

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  • Soizic Garaud

    (Université Libre de Bruxelles)

  • Marie-Caroline Dieu-Nosjean

    (Sorbonne University UMRS1135, Inserm U1135, Laboratory “Immune microenvironment and immunotherapy”, Centre d’Immunologie et des Maladies Infectieuses Paris (CIMI-Paris))

  • Karen Willard-Gallo

    (Université Libre de Bruxelles)

Abstract

Tumor-infiltrating lymphocytes (TILs) are critical in the elimination of cancer cells, a concept highlighted by recent advances in cancer immunotherapy. Significant evidence reveals that their organization in tertiary lymphoid structures together with specific subpopulation composition/balances stimulates cellular crosstalk and anti-tumor immunity in patients.

Suggested Citation

  • Soizic Garaud & Marie-Caroline Dieu-Nosjean & Karen Willard-Gallo, 2022. "T follicular helper and B cell crosstalk in tertiary lymphoid structures and cancer immunotherapy," Nature Communications, Nature, vol. 13(1), pages 1-4, December.
    • Handle: RePEc:nat:natcom:v:13:y:2022:i:1:d:10.1038_s41467-022-29753-z
    DOI: 10.1038/s41467-022-29753-z
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    References listed on IDEAS

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    1. Lenka Kasikova & Jana Rakova & Michal Hensler & Tereza Lanickova & Jana Tomankova & Josef Pasulka & Jana Drozenova & Katerina Mojzisova & Anna Fialova & Sarka Vosahlikova & Jan Laco & Ales Ryska & Pav, 2024. "Tertiary lymphoid structures and B cells determine clinically relevant T cell phenotypes in ovarian cancer," Nature Communications, Nature, vol. 15(1), pages 1-19, December.

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