IDEAS home Printed from https://ideas.repec.org/a/nat/natcom/v12y2021i1d10.1038_s41467-021-26795-7.html
   My bibliography  Save this article

The parent-of-origin lncRNA MISSEN regulates rice endosperm development

Author

Listed:
  • Yan-Fei Zhou

    (Sun Yat-Sen University)

  • Yu-Chan Zhang

    (Sun Yat-Sen University)

  • Yu-Meng Sun

    (Sun Yat-Sen University)

  • Yang Yu

    (Sun Yat-Sen University)

  • Meng-Qi Lei

    (Sun Yat-Sen University)

  • Yu-Wei Yang

    (Sun Yat-Sen University)

  • Jian-Ping Lian

    (Sun Yat-Sen University)

  • Yan-Zhao Feng

    (Sun Yat-Sen University)

  • Zhi Zhang

    (Sun Yat-Sen University)

  • Lu Yang

    (Sun Yat-Sen University)

  • Rui-Rui He

    (Sun Yat-Sen University)

  • Jia-Hui Huang

    (Sun Yat-Sen University)

  • Yu Cheng

    (Sun Yat-Sen University)

  • Yu-Wei Liu

    (Sun Yat-Sen University)

  • Yue-Qin Chen

    (Sun Yat-Sen University
    Sun Yat-sen University)

Abstract

The cereal endosperm is a major factor determining seed size and shape. However, the molecular mechanisms of endosperm development are not fully understood. Long noncoding RNAs (lncRNAs) function in various biological processes. Here we show a lncRNA, MISSEN, that plays an essential role in early endosperm development in rice (Oryza sativa). MISSEN is a parent-of-origin lncRNA expressed in endosperm, and negatively regulates endosperm development, leading to a prominent dent and bulge in the seed. Mechanistically, MISSEN functions through hijacking a helicase family protein (HeFP) to regulate tubulin function during endosperm nucleus division and endosperm cellularization, resulting in abnormal cytoskeletal polymerization. Finally, we revealed that the expression of MISSEN is inhibited by histone H3 lysine 27 trimethylation (H3K27me3) modification after pollination. Therefore, MISSEN is the first lncRNA identified as a regulator in endosperm development, highlighting the potential applications in rice breeding.

Suggested Citation

  • Yan-Fei Zhou & Yu-Chan Zhang & Yu-Meng Sun & Yang Yu & Meng-Qi Lei & Yu-Wei Yang & Jian-Ping Lian & Yan-Zhao Feng & Zhi Zhang & Lu Yang & Rui-Rui He & Jia-Hui Huang & Yu Cheng & Yu-Wei Liu & Yue-Qin C, 2021. "The parent-of-origin lncRNA MISSEN regulates rice endosperm development," Nature Communications, Nature, vol. 12(1), pages 1-14, December.
    • Handle: RePEc:nat:natcom:v:12:y:2021:i:1:d:10.1038_s41467-021-26795-7
    DOI: 10.1038/s41467-021-26795-7
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/s41467-021-26795-7
    File Function: Abstract
    Download Restriction: no
    File URL: https://libkey.io/10.1038/s41467-021-26795-7?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:natcom:v:12:y:2021:i:1:d:10.1038_s41467-021-26795-7. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.