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Design of COVID-19 staged alert systems to ensure healthcare capacity with minimal closures

Author

Listed:
  • Haoxiang Yang

    (Los Alamos National Laboratory)

  • Özge Sürer

    (Northwestern University)

  • Daniel Duque

    (Northwestern University)

  • David P. Morton

    (Northwestern University)

  • Bismark Singh

    (Friedrich-Alexander-Universität Erlangen-Nürnberg)

  • Spencer J. Fox

    (The University of Texas at Austin)

  • Remy Pasco

    (The University of Texas at Austin)

  • Kelly Pierce

    (The University of Texas at Austin)

  • Paul Rathouz

    (The University of Texas at Austin)

  • Victoria Valencia

    (The University of Texas at Austin)

  • Zhanwei Du

    (The University of Texas at Austin)

  • Michael Pignone

    (The University of Texas at Austin)

  • Mark E. Escott

    (The City of Austin)

  • Stephen I. Adler

    (The City of Austin)

  • S. Claiborne Johnston

    (The University of Texas at Austin)

  • Lauren Ancel Meyers

    (The University of Texas at Austin
    Santa Fe Institute)

Abstract

Community mitigation strategies to combat COVID-19, ranging from healthy hygiene to shelter-in-place orders, exact substantial socioeconomic costs. Judicious implementation and relaxation of restrictions amplify their public health benefits while reducing costs. We derive optimal strategies for toggling between mitigation stages using daily COVID-19 hospital admissions. With public compliance, the policy triggers ensure adequate intensive care unit capacity with high probability while minimizing the duration of strict mitigation measures. In comparison, we show that other sensible COVID-19 staging policies, including France’s ICU-based thresholds and a widely adopted indicator for reopening schools and businesses, require overly restrictive measures or trigger strict stages too late to avert catastrophic surges. As proof-of-concept, we describe the optimization and maintenance of the staged alert system that has guided COVID-19 policy in a large US city (Austin, Texas) since May 2020. As cities worldwide face future pandemic waves, our findings provide a robust strategy for tracking COVID-19 hospital admissions as an early indicator of hospital surges and enacting staged measures to ensure integrity of the health system, safety of the health workforce, and public confidence.

Suggested Citation

  • Haoxiang Yang & Özge Sürer & Daniel Duque & David P. Morton & Bismark Singh & Spencer J. Fox & Remy Pasco & Kelly Pierce & Paul Rathouz & Victoria Valencia & Zhanwei Du & Michael Pignone & Mark E. Esc, 2021. "Design of COVID-19 staged alert systems to ensure healthcare capacity with minimal closures," Nature Communications, Nature, vol. 12(1), pages 1-7, December.
  • Handle: RePEc:nat:natcom:v:12:y:2021:i:1:d:10.1038_s41467-021-23989-x
    DOI: 10.1038/s41467-021-23989-x
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    Cited by:

    1. Emily Howerton & Lucie Contamin & Luke C. Mullany & Michelle Qin & Nicholas G. Reich & Samantha Bents & Rebecca K. Borchering & Sung-mok Jung & Sara L. Loo & Claire P. Smith & John Levander & Jessica , 2023. "Evaluation of the US COVID-19 Scenario Modeling Hub for informing pandemic response under uncertainty," Nature Communications, Nature, vol. 14(1), pages 1-15, December.
    2. Robin L. Dillon & Vicki M. Bier & Richard Sheffield John & Abdullah Althenayyan, 2023. "Closing the Gap Between Decision Analysis and Policy Analysts Before the Next Pandemic," Decision Analysis, INFORMS, vol. 20(2), pages 109-132, June.
    3. Reese Richardson & Emile Jorgensen & Philip Arevalo & Tobias M. Holden & Katelyn M. Gostic & Massimo Pacilli & Isaac Ghinai & Shannon Lightner & Sarah Cobey & Jaline Gerardin, 2022. "Tracking changes in SARS-CoV-2 transmission with a novel outpatient sentinel surveillance system in Chicago, USA," Nature Communications, Nature, vol. 13(1), pages 1-10, December.

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