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Degradable polymeric vehicles for postoperative pain management

Author

Listed:
  • Natasha C. Brigham

    (Duke University)

  • Ru-Rong Ji

    (Duke University
    Duke University)

  • Matthew L. Becker

    (Duke University
    Duke University
    Duke University
    Duke University)

Abstract

Effective control of pain management has the potential to significantly decrease the need for prescription opioids following a surgical procedure. While extended release products for pain management are available commercially, the implementation of a device that safely and reliably provides extended analgesia and is sufficiently flexible to facilitate a diverse array of release profiles would serve to advance patient comfort, quality of care and compliance following surgical procedures. Herein, we review current polymeric systems that could be utilized in new, controlled post-operative pain management devices and highlight where opportunities for improvement exist.

Suggested Citation

  • Natasha C. Brigham & Ru-Rong Ji & Matthew L. Becker, 2021. "Degradable polymeric vehicles for postoperative pain management," Nature Communications, Nature, vol. 12(1), pages 1-13, December.
    • Handle: RePEc:nat:natcom:v:12:y:2021:i:1:d:10.1038_s41467-021-21438-3
    DOI: 10.1038/s41467-021-21438-3
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    Cited by:

    1. Pauric Bannigan & Zeqing Bao & Riley J. Hickman & Matteo Aldeghi & Florian Häse & Alán Aspuru-Guzik & Christine Allen, 2023. "Machine learning models to accelerate the design of polymeric long-acting injectables," Nature Communications, Nature, vol. 14(1), pages 1-12, December.

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