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Reproductive phasiRNAs regulate reprogramming of gene expression and meiotic progression in rice

Author

Listed:
  • Yu-Chan Zhang

    (Sun Yat-Sen University)

  • Meng-Qi Lei

    (Sun Yat-Sen University)

  • Yan-Fei Zhou

    (Sun Yat-Sen University)

  • Yu-Wei Yang

    (Sun Yat-Sen University)

  • Jian-Ping Lian

    (Sun Yat-Sen University)

  • Yang Yu

    (Sun Yat-Sen University)

  • Yan-Zhao Feng

    (Sun Yat-Sen University)

  • Ke-Ren Zhou

    (Sun Yat-Sen University)

  • Rui-Rui He

    (Sun Yat-Sen University)

  • Huang He

    (Sun Yat-Sen University)

  • Zhi Zhang

    (Sun Yat-Sen University)

  • Jian-Hua Yang

    (Sun Yat-Sen University)

  • Yue-Qin Chen

    (Sun Yat-Sen University
    Guangdong Laboratory of Lingnan Modern Agriculture)

Abstract

Plant spermatogenesis is a complex process that directly affects crop breeding. A rapid change in gene abundance occurs at early meiosis prophase, when gene regulation is selective. However, how these genes are regulated remains unknown. Here, we show that rice reproductive phasiRNAs are essential for the elimination of a specific set of RNAs during meiotic prophase I. These phasiRNAs cleave target mRNAs in a regulatory manner such that one phasiRNA can target more than one gene, and/or a single gene can be targeted by more than one phasiRNA to efficiently silence target genes. Our investigation of phasiRNA-knockdown and PHAS-edited transgenic plants demonstrates that phasiRNAs and their nucleotide variations are required for meiosis progression and fertility. This study highlights the importance of reproductive phasiRNAs for the reprogramming of gene expression during meiotic progression and establishes a basis for future studies on the roles of phasiRNAs with a goal of crop improvement.

Suggested Citation

  • Yu-Chan Zhang & Meng-Qi Lei & Yan-Fei Zhou & Yu-Wei Yang & Jian-Ping Lian & Yang Yu & Yan-Zhao Feng & Ke-Ren Zhou & Rui-Rui He & Huang He & Zhi Zhang & Jian-Hua Yang & Yue-Qin Chen, 2020. "Reproductive phasiRNAs regulate reprogramming of gene expression and meiotic progression in rice," Nature Communications, Nature, vol. 11(1), pages 1-11, December.
  • Handle: RePEc:nat:natcom:v:11:y:2020:i:1:d:10.1038_s41467-020-19922-3
    DOI: 10.1038/s41467-020-19922-3
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    Cited by:

    1. Hinako Tamotsu & Koji Koizumi & Alejandro Villar Briones & Reina Komiya, 2023. "Spatial distribution of three ARGONAUTEs regulates the anther phasiRNA pathway," Nature Communications, Nature, vol. 14(1), pages 1-11, December.
    2. Fuxi Rong & Yusong Lv & Pingchuan Deng & Xia Wu & Yaqi Zhang & Erkui Yue & Yuxin Shen & Sajid Muhammad & Fangrui Ni & Hongwu Bian & Xiangjin Wei & Weijun Zhou & Peisong Hu & Liang Wu, 2024. "Switching action modes of miR408-5p mediates auxin signaling in rice," Nature Communications, Nature, vol. 15(1), pages 1-17, December.

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