IDEAS home Printed from https://ideas.repec.org/a/nat/natcom/v11y2020i1d10.1038_s41467-020-19326-3.html
   My bibliography  Save this article

Extensive 5′-surveillance guards against non-canonical NAD-caps of nuclear mRNAs in yeast

Author

Listed:
  • Yaqing Zhang

    (Heidelberg University)

  • David Kuster

    (Heidelberg University)

  • Tobias Schmidt

    (German Cancer Research Center (DKFZ))

  • Daniel Kirrmaier

    (Heidelberg University
    German Cancer Research Center (DKFZ), DKFZ-ZMBH Alliance)

  • Gabriele Nübel

    (Heidelberg University)

  • David Ibberson

    (Heidelberg University)

  • Vladimir Benes

    (European Molecular Biology Laboratory (EMBL))

  • Hans Hombauer

    (German Cancer Research Center (DKFZ)
    Heidelberg University)

  • Michael Knop

    (Heidelberg University
    German Cancer Research Center (DKFZ), DKFZ-ZMBH Alliance)

  • Andres Jäschke

    (Heidelberg University)

Abstract

The ubiquitous redox coenzyme nicotinamide adenine dinucleotide (NAD) acts as a non-canonical cap structure on prokaryotic and eukaryotic ribonucleic acids. Here we find that in budding yeast, NAD-RNAs are abundant (>1400 species), short (

Suggested Citation

  • Yaqing Zhang & David Kuster & Tobias Schmidt & Daniel Kirrmaier & Gabriele Nübel & David Ibberson & Vladimir Benes & Hans Hombauer & Michael Knop & Andres Jäschke, 2020. "Extensive 5′-surveillance guards against non-canonical NAD-caps of nuclear mRNAs in yeast," Nature Communications, Nature, vol. 11(1), pages 1-17, December.
    • Handle: RePEc:nat:natcom:v:11:y:2020:i:1:d:10.1038_s41467-020-19326-3
    DOI: 10.1038/s41467-020-19326-3
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/s41467-020-19326-3
    File Function: Abstract
    Download Restriction: no
    File URL: https://libkey.io/10.1038/s41467-020-19326-3?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Sunny Sharma & Jun Yang & Ewa Grudzien-Nogalska & Jessica Shivas & Kelvin Y. Kwan & Megerditch Kiledjian, 2022. "Xrn1 is a deNADding enzyme modulating mitochondrial NAD-capped RNA," Nature Communications, Nature, vol. 13(1), pages 1-11, December.
    2. José Vicente Gomes-Filho & Ruth Breuer & Hector Gabriel Morales-Filloy & Nadiia Pozhydaieva & Andreas Borst & Nicole Paczia & Jörg Soppa & Katharina Höfer & Andres Jäschke & Lennart Randau, 2023. "Identification of NAD-RNA species and ADPR-RNA decapping in Archaea," Nature Communications, Nature, vol. 14(1), pages 1-12, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:natcom:v:11:y:2020:i:1:d:10.1038_s41467-020-19326-3. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.