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The tomato receptor CuRe1 senses a cell wall protein to identify Cuscuta as a pathogen

Author

Listed:
  • Volker Hegenauer

    (Molecular Plant Physiology
    Center for Plant Molecular Biology)

  • Peter Slaby

    (Molecular Plant Physiology)

  • Max Körner

    (Molecular Plant Physiology)

  • Julien-Alexander Bruckmüller

    (Department of Arctic and Marine Biology
    Solana Research GmbH)

  • Ronja Burggraf

    (Center for Plant Molecular Biology)

  • Isabell Albert

    (Molecular Plant Physiology)

  • Bettina Kaiser

    (Center for Plant Molecular Biology)

  • Birgit Löffelhardt

    (Center for Plant Molecular Biology)

  • Irina Droste-Borel

    (Quantitative Proteomics & Proteome Center Tübingen)

  • Jan Sklenar

    (University of East Anglia)

  • Frank L. H. Menke

    (University of East Anglia)

  • Boris Maček

    (Quantitative Proteomics & Proteome Center Tübingen)

  • Aashish Ranjan

    (College of Biological Sciences, UC Davis
    National Institute of Plant Genome Research)

  • Neelima Sinha

    (College of Biological Sciences, UC Davis)

  • Thorsten Nürnberger

    (Center for Plant Molecular Biology
    University of Johannesburg)

  • Georg Felix

    (Center for Plant Molecular Biology)

  • Kirsten Krause

    (Department of Arctic and Marine Biology)

  • Mark Stahl

    (Center for Plant Molecular Biology)

  • Markus Albert

    (Molecular Plant Physiology)

Abstract

Parasitic plants of the genus Cuscuta penetrate shoots of host plants with haustoria and build a connection to the host vasculature to exhaust water, solutes and carbohydrates. Such infections usually stay unrecognized by the host and lead to harmful host plant damage. Here, we show a molecular mechanism of how plants can sense parasitic Cuscuta. We isolated an 11 kDa protein of the parasite cell wall and identified it as a glycine-rich protein (GRP). This GRP, as well as its minimal peptide epitope Crip21, serve as a pathogen-associated molecular pattern and specifically bind and activate a membrane-bound immune receptor of tomato, the Cuscuta Receptor 1 (CuRe1), leading to defense responses in resistant hosts. These findings provide the initial steps to understand the resistance mechanisms against parasitic plants and further offer great potential for protecting crops by engineering resistance against parasitic plants.

Suggested Citation

  • Volker Hegenauer & Peter Slaby & Max Körner & Julien-Alexander Bruckmüller & Ronja Burggraf & Isabell Albert & Bettina Kaiser & Birgit Löffelhardt & Irina Droste-Borel & Jan Sklenar & Frank L. H. Menk, 2020. "The tomato receptor CuRe1 senses a cell wall protein to identify Cuscuta as a pathogen," Nature Communications, Nature, vol. 11(1), pages 1-7, December.
    • Handle: RePEc:nat:natcom:v:11:y:2020:i:1:d:10.1038_s41467-020-19147-4
    DOI: 10.1038/s41467-020-19147-4
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    Cited by:

    1. Li Fan & Katja Fröhlich & Eric Melzer & Rory N. Pruitt & Isabell Albert & Lisha Zhang & Anna Joe & Chenlei Hua & Yanyue Song & Markus Albert & Sang-Tae Kim & Detlef Weigel & Cyril Zipfel & Eunyoung Ch, 2022. "Genotyping-by-sequencing-based identification of Arabidopsis pattern recognition receptor RLP32 recognizing proteobacterial translation initiation factor IF1," Nature Communications, Nature, vol. 13(1), pages 1-13, December.

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