IDEAS home Printed from https://ideas.repec.org/a/nat/natcom/v11y2020i1d10.1038_s41467-020-17318-x.html
   My bibliography  Save this article

Seroprevalence of antibodies against SARS-CoV-2 among health care workers in a large Spanish reference hospital

Author

Listed:
  • Alberto L. Garcia-Basteiro

    (Hospital Clínic - Universitat de Barcelona
    Hospital Clínic, Universitat de Barcelona
    Centro de Investigação em Saúde de Manhiça (CISM))

  • Gemma Moncunill

    (Hospital Clínic - Universitat de Barcelona)

  • Marta Tortajada

    (Hospital Clínic, Universitat de Barcelona)

  • Marta Vidal

    (Hospital Clínic - Universitat de Barcelona)

  • Caterina Guinovart

    (Hospital Clínic - Universitat de Barcelona)

  • Alfons Jiménez

    (Hospital Clínic - Universitat de Barcelona
    Spanish Consortium for Research in Epidemiology and Public Health (CIBERESP))

  • Rebeca Santano

    (Hospital Clínic - Universitat de Barcelona)

  • Sergi Sanz

    (Hospital Clínic - Universitat de Barcelona
    Spanish Consortium for Research in Epidemiology and Public Health (CIBERESP)
    Faculty of Medicine, Universitat de Barcelona)

  • Susana Méndez

    (Hospital Clínic - Universitat de Barcelona
    Spanish Consortium for Research in Epidemiology and Public Health (CIBERESP))

  • Anna Llupià

    (Hospital Clínic - Universitat de Barcelona
    Hospital Clinic, Universitat de Barcelona)

  • Ruth Aguilar

    (Hospital Clínic - Universitat de Barcelona)

  • Selena Alonso

    (Hospital Clínic - Universitat de Barcelona)

  • Diana Barrios

    (Hospital Clínic - Universitat de Barcelona)

  • Carlo Carolis

    (The Barcelona Institute of Science and Technology)

  • Pau Cisteró

    (Hospital Clínic - Universitat de Barcelona)

  • Eugenia Chóliz

    (Universitat de Barcelona)

  • Angeline Cruz

    (Hospital Clínic - Universitat de Barcelona)

  • Silvia Fochs

    (Hospital Clínic - Universitat de Barcelona)

  • Chenjerai Jairoce

    (Hospital Clínic - Universitat de Barcelona
    Centro de Investigação em Saúde de Manhiça (CISM))

  • Jochen Hecht

    (The Barcelona Institute of Science and Technology)

  • Montserrat Lamoglia

    (Hospital Clínic - Universitat de Barcelona
    Universitat Ramon Llull de Barcelona)

  • Mikel J. Martínez

    (Hospital Clínic - Universitat de Barcelona
    Hospital Clinic, Universitat de Barcelona)

  • Robert A. Mitchell

    (Hospital Clínic - Universitat de Barcelona)

  • Natalia Ortega

    (Hospital Clínic - Universitat de Barcelona)

  • Nuria Pey

    (Hospital Clínic - Universitat de Barcelona)

  • Laura Puyol

    (Hospital Clínic - Universitat de Barcelona)

  • Marta Ribes

    (Hospital Clínic - Universitat de Barcelona)

  • Neus Rosell

    (Hospital Clínic - Universitat de Barcelona)

  • Patricia Sotomayor

    (Hospital Clínic - Universitat de Barcelona)

  • Sara Torres

    (Hospital Clínic - Universitat de Barcelona)

  • Sarah Williams

    (Hospital Clínic - Universitat de Barcelona)

  • Sonia Barroso

    (Hospital Clínic, Universitat de Barcelona)

  • Anna Vilella

    (Hospital Clínic - Universitat de Barcelona
    Hospital Clinic, Universitat de Barcelona)

  • José Muñoz

    (Hospital Clínic - Universitat de Barcelona
    Hospital Clínic, Universitat de Barcelona)

  • Antoni Trilla

    (Hospital Clínic - Universitat de Barcelona
    Hospital Clinic, Universitat de Barcelona
    Universitat de Barcelona)

  • Pilar Varela

    (Hospital Clínic, Universitat de Barcelona)

  • Alfredo Mayor

    (Hospital Clínic - Universitat de Barcelona
    Centro de Investigação em Saúde de Manhiça (CISM)
    Spanish Consortium for Research in Epidemiology and Public Health (CIBERESP))

  • Carlota Dobaño

    (Hospital Clínic - Universitat de Barcelona
    Spanish Consortium for Research in Epidemiology and Public Health (CIBERESP))

Abstract

Health care workers (HCW) are a high-risk population to acquire SARS-CoV-2 infection from patients or other fellow HCW. This study aims at estimating the seroprevalence against SARS-CoV-2 in a random sample of HCW from a large hospital in Spain. Of the 578 participants recruited from 28 March to 9 April 2020, 54 (9.3%, 95% CI: 7.1–12.0) were seropositive for IgM and/or IgG and/or IgA against SARS-CoV-2. The cumulative prevalence of SARS-CoV-2 infection (presence of antibodies or past or current positive rRT-PCR) was 11.2% (65/578, 95% CI: 8.8–14.1). Among those with evidence of past or current infection, 40.0% (26/65) had not been previously diagnosed with COVID-19. Here we report a relatively low seroprevalence of antibodies among HCW at the peak of the COVID-19 epidemic in Spain. A large proportion of HCW with past or present infection had not been previously diagnosed with COVID-19, which calls for active periodic rRT-PCR testing in hospital settings.

Suggested Citation

  • Alberto L. Garcia-Basteiro & Gemma Moncunill & Marta Tortajada & Marta Vidal & Caterina Guinovart & Alfons Jiménez & Rebeca Santano & Sergi Sanz & Susana Méndez & Anna Llupià & Ruth Aguilar & Selena A, 2020. "Seroprevalence of antibodies against SARS-CoV-2 among health care workers in a large Spanish reference hospital," Nature Communications, Nature, vol. 11(1), pages 1-9, December.
    • Handle: RePEc:nat:natcom:v:11:y:2020:i:1:d:10.1038_s41467-020-17318-x
    DOI: 10.1038/s41467-020-17318-x
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/s41467-020-17318-x
    File Function: Abstract
    Download Restriction: no
    File URL: https://libkey.io/10.1038/s41467-020-17318-x?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Maryam Yaghoubi & Mohammad Salimi & Mohammad Meskarpour‐Amiri, 2022. "Systematic review of productivity loss among healthcare workers due to Covid‐19," International Journal of Health Planning and Management, Wiley Blackwell, vol. 37(1), pages 94-111, January.
    2. Nathan Post & Danielle Eddy & Catherine Huntley & May C I van Schalkwyk & Madhumita Shrotri & David Leeman & Samuel Rigby & Sarah V Williams & William H Bermingham & Paul Kellam & John Maher & Adrian , 2020. "Antibody response to SARS-CoV-2 infection in humans: A systematic review," PLOS ONE, Public Library of Science, vol. 15(12), pages 1-27, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:natcom:v:11:y:2020:i:1:d:10.1038_s41467-020-17318-x. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.