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Microbiota-derived acetate protects against respiratory syncytial virus infection through a GPR43-type 1 interferon response

Author

Listed:
  • Krist Helen Antunes

    (Pontifical Catholic University of Rio Grande do Sul)

  • José Luís Fachi

    (University of Campinas)

  • Rosemeire Paula

    (University of Campinas)

  • Emanuelle Fraga Silva

    (Pontifical Catholic University of Rio Grande do Sul)

  • Laís Passariello Pral

    (University of Campinas)

  • Adara Áurea Santos

    (Universidade Federal de Santa Catarina)

  • Greicy Brisa Malaquias Dias

    (Universidade Federal de Santa Catarina)

  • José Eduardo Vargas

    (Passo Fundo University)

  • Renato Puga

    (Hospital Israelita Albert Einstein HIAE)

  • Fabiana Quoos Mayer

    (Secretariat of Agriculture, Livestock and Irrigation)

  • Fábio Maito

    (Pontifical Catholic University of Rio Grande do Sul)

  • Carlos R. Zárate-Bladés

    (Federal University of Santa Catarina, UFSC)

  • Nadim J. Ajami

    (Baylor College of Medicine)

  • Marcella Ramos Sant’Ana

    (University of Campinas)

  • Thamiris Candreva

    (University of Campinas)

  • Hosana Gomes Rodrigues

    (University of Campinas)

  • Marcio Schmiele

    (Federal University of Jequitinhonha and Mucuri Valleys (UFVJM))

  • Maria Teresa Pedrosa Silva Clerici

    (University of Campinas (UNICAMP) – Cidade Universitária Zeferino Vaz, Monteiro Lobato, 80)

  • José Luiz Proença-Modena

    (University of Campinas)

  • Angélica Thomas Vieira

    (Federal University of Minas Gerais)

  • Charles R. Mackay

    (Monash University)

  • Daniel Mansur

    (Universidade Federal de Santa Catarina)

  • Mauricio T. Caballero

    (Fundación INFANT)

  • Jacqui Marzec

    (National Institute of Environmental Health Sciences (NIEHS), NIH, Research Triangle)

  • Jianying Li

    (National Institute of Environmental Health Sciences (NIEHS), NIH, Research Triangle)

  • Xuting Wang

    (National Institute of Environmental Health Sciences (NIEHS), NIH, Research Triangle)

  • Douglas Bell

    (National Institute of Environmental Health Sciences (NIEHS), NIH, Research Triangle)

  • Fernando P. Polack

    (Fundación INFANT
    Vanderbilt University, EUA)

  • Steven R. Kleeberger

    (National Institute of Environmental Health Sciences (NIEHS), NIH, Research Triangle)

  • Renato T. Stein

    (São Lucas Hospital PUCRS)

  • Marco Aurélio Ramirez Vinolo

    (University of Campinas)

  • Ana Paula Duarte Souza

    (Pontifical Catholic University of Rio Grande do Sul
    School of Heath Science, PUCRS)

Abstract

Severe respiratory syncytial virus (RSV) infection is a major cause of morbidity and mortality in infants

Suggested Citation

  • Krist Helen Antunes & José Luís Fachi & Rosemeire Paula & Emanuelle Fraga Silva & Laís Passariello Pral & Adara Áurea Santos & Greicy Brisa Malaquias Dias & José Eduardo Vargas & Renato Puga & Fabiana, 2019. "Microbiota-derived acetate protects against respiratory syncytial virus infection through a GPR43-type 1 interferon response," Nature Communications, Nature, vol. 10(1), pages 1-17, December.
  • Handle: RePEc:nat:natcom:v:10:y:2019:i:1:d:10.1038_s41467-019-11152-6
    DOI: 10.1038/s41467-019-11152-6
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    Cited by:

    1. Patrick J. Dörner & Harithaa Anandakumar & Ivo Röwekamp & Facundo Fiocca Vernengo & Belén Millet Pascual-Leone & Marta Krzanowski & Josua Sellmaier & Ulrike Brüning & Raphaela Fritsche-Guenther & Lenn, 2024. "Clinically used broad-spectrum antibiotics compromise inflammatory monocyte-dependent antibacterial defense in the lung," Nature Communications, Nature, vol. 15(1), pages 1-14, December.
    2. Junling Niu & Mengmeng Cui & Xin Yang & Juan Li & Yuhui Yao & Qiuhong Guo & Ailing Lu & Xiaopeng Qi & Dongming Zhou & Chenhong Zhang & Liping Zhao & Guangxun Meng, 2023. "Microbiota-derived acetate enhances host antiviral response via NLRP3," Nature Communications, Nature, vol. 14(1), pages 1-17, December.

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