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Full-field structured-illumination super-resolution X-ray transmission microscopy

Author

Listed:
  • Benedikt Günther

    (Technical University of Munich
    Technical University of Munich
    Max-Planck-Institute of Quantum Optics)

  • Lorenz Hehn

    (Technical University of Munich
    Technical University of Munich
    Technical University of Munich)

  • Christoph Jud

    (Technical University of Munich
    Technical University of Munich)

  • Alexander Hipp

    (Helmholtz-Zentrum Geesthacht)

  • Martin Dierolf

    (Technical University of Munich
    Technical University of Munich)

  • Franz Pfeiffer

    (Technical University of Munich
    Technical University of Munich
    Technical University of Munich)

Abstract

Modern transmission X-ray microscopy techniques provide very high resolution at low and medium X-ray energies, but suffer from a limited field-of-view. If sub-micrometre resolution is desired, their field-of-view is typically limited to less than one millimetre. Although the field-of-view increases through combining multiple images from adjacent regions of the specimen, so does the required data acquisition time. Here, we present a method for fast full-field super-resolution transmission microscopy by structured illumination of the specimen. This technique is well-suited even for hard X-ray energies above 30 keV, where efficient optics are hard to obtain. Accordingly, investigation of optically thick specimen becomes possible with our method combining a wide field-of-view spanning multiple millimetres, or even centimetres, with sub-micron resolution and hard X-ray energies.

Suggested Citation

  • Benedikt Günther & Lorenz Hehn & Christoph Jud & Alexander Hipp & Martin Dierolf & Franz Pfeiffer, 2019. "Full-field structured-illumination super-resolution X-ray transmission microscopy," Nature Communications, Nature, vol. 10(1), pages 1-7, December.
  • Handle: RePEc:nat:natcom:v:10:y:2019:i:1:d:10.1038_s41467-019-10537-x
    DOI: 10.1038/s41467-019-10537-x
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