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Biosynthesis of DHGA12 and its roles in Arabidopsis seedling establishment

Author

Listed:
  • Hao Liu

    (Henan University
    Henan University)

  • Siyi Guo

    (Henan University
    Henan University)

  • Minghua Lu

    (Henan University)

  • Yu Zhang

    (Henan University
    Henan University)

  • Junhua Li

    (Henan Normal University)

  • Wei Wang

    (Henan University
    Henan University)

  • Pengtao Wang

    (Henan University
    Henan University)

  • Junli Zhang

    (Henan University
    Henan University)

  • Zhubing Hu

    (Henan University
    Henan University)

  • Liangliang Li

    (Henan University
    Henan University)

  • Lingyu Si

    (Henan University
    Henan University)

  • Jie Zhang

    (Henan University
    Henan University)

  • Qi Qi

    (Beijing Forestry University)

  • Xiangning Jiang

    (Beijing Forestry University)

  • José Ramón Botella

    (Henan University
    Henan University
    The University of Queensland)

  • Hua Wang

    (Henan University)

  • Chun-Peng Song

    (Henan University
    Henan University)

Abstract

Seed germination and photoautotrophic establishment are controlled by the antagonistic activity of the phytohormones gibberellins (GAs) and abscisic acid (ABA). Here we show that Arabidopsis thaliana GAS2 (Gain of Function in ABA-modulated Seed Germination 2), a protein belonging to the Fe-dependent 2-oxoglutarate dioxygenase superfamily, catalyzes the stereospecific hydration of GA12 to produce GA12 16, 17-dihydro-16α-ol (DHGA12). We show that DHGA12, a C20-GA has an atypical structure compared to known active GAs but can bind to the GA receptor (GID1c). DHGA12 can promote seed germination, hypocotyl elongation and cotyledon greening. Silencing and over-expression of GAS2 alters the ABA/GA ratio and sensitivity to ABA during seed germination and photoautotrophic establishment. Hence, we propose that GAS2 acts to modulate hormonal balance during early seedling development.

Suggested Citation

  • Hao Liu & Siyi Guo & Minghua Lu & Yu Zhang & Junhua Li & Wei Wang & Pengtao Wang & Junli Zhang & Zhubing Hu & Liangliang Li & Lingyu Si & Jie Zhang & Qi Qi & Xiangning Jiang & José Ramón Botella & Hua, 2019. "Biosynthesis of DHGA12 and its roles in Arabidopsis seedling establishment," Nature Communications, Nature, vol. 10(1), pages 1-14, December.
    • Handle: RePEc:nat:natcom:v:10:y:2019:i:1:d:10.1038_s41467-019-09467-5
    DOI: 10.1038/s41467-019-09467-5
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    Cited by:

    1. Theo Lange & Nadiem Atiq & Maria João Pimenta Lange, 2023. "GAS2 encodes a 2-oxoglutarate dependent dioxygenase involved in ABA catabolism," Nature Communications, Nature, vol. 14(1), pages 1-4, December.

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