IDEAS home Printed from https://ideas.repec.org/a/nat/natcom/v10y2019i1d10.1038_s41467-019-09253-3.html
   My bibliography  Save this article

Coming together to define membrane contact sites

Author

Listed:
  • Luca Scorrano

    (University of Padua)

  • Maria Antonietta Matteis

    (Telethon Institute of Genetics and Medicine
    University of Napoli Federico II)

  • Scott Emr

    (Cornell University)

  • Francesca Giordano

    (Paris-Saclay University)

  • György Hajnóczky

    (Thomas Jefferson University)

  • Benoît Kornmann

    (University of Oxford, Department of Biochemistry)

  • Laura L. Lackner

    (Northwestern University)

  • Tim P. Levine

    (UCL Institute of Ophthalmology)

  • Luca Pellegrini

    (Universitè Laval)

  • Karin Reinisch

    (Yale University School of Medicine)

  • Rosario Rizzuto

    (University of Padua)

  • Thomas Simmen

    (Department of Cell Biology)

  • Harald Stenmark

    (University of Oslo, Montebello)

  • Christian Ungermann

    (University of Osnabrück)

  • Maya Schuldiner

    (Weizmann Institute of Science)

Abstract

Close proximities between organelles have been described for decades. However, only recently a specific field dealing with organelle communication at membrane contact sites has gained wide acceptance, attracting scientists from multiple areas of cell biology. The diversity of approaches warrants a unified vocabulary for the field. Such definitions would facilitate laying the foundations of this field, streamlining communication and resolving semantic controversies. This opinion, written by a panel of experts in the field, aims to provide this burgeoning area with guidelines for the experimental definition and analysis of contact sites. It also includes suggestions on how to operationally and tractably measure and analyze them with the hope of ultimately facilitating knowledge production and dissemination within and outside the field of contact-site research.

Suggested Citation

  • Luca Scorrano & Maria Antonietta Matteis & Scott Emr & Francesca Giordano & György Hajnóczky & Benoît Kornmann & Laura L. Lackner & Tim P. Levine & Luca Pellegrini & Karin Reinisch & Rosario Rizzuto &, 2019. "Coming together to define membrane contact sites," Nature Communications, Nature, vol. 10(1), pages 1-11, December.
    • Handle: RePEc:nat:natcom:v:10:y:2019:i:1:d:10.1038_s41467-019-09253-3
    DOI: 10.1038/s41467-019-09253-3
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/s41467-019-09253-3
    File Function: Abstract
    Download Restriction: no
    File URL: https://libkey.io/10.1038/s41467-019-09253-3?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Patrick A. Sandoz & Robin A. Denhardt-Eriksson & Laurence Abrami & Luciano A. Abriata & Gard Spreemann & Catherine Maclachlan & Sylvia Ho & Béatrice Kunz & Kathryn Hess & Graham Knott & Francisco S. M, 2023. "Dynamics of CLIMP-63 S-acylation control ER morphology," Nature Communications, Nature, vol. 14(1), pages 1-17, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:natcom:v:10:y:2019:i:1:d:10.1038_s41467-019-09253-3. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.