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Reactions with Visnaginone: Synthesis, Cyclisation and Microbial Evaluation of Some Visnaginone Thiosemicarbazone Derivatives

Author

Listed:
  • Sadek Abdou
  • Salah El-Qusy
  • Sami Ghabrial
  • Mahmoud Haggag

Abstract

Several new visnaginone ethers were prepared and their thiosemicarbazone derivatives are synthesized. The behavior of the thiosemicarbazones in methanolic sodium methoxide and hydrochloric acid is discussed. Structures were established on the bases of elemental and spectral data studies. Some of the thiosemicarbazones were tested for their antimicrobial activity. The structures of the synthesized derivatives (5a-g,6a-g) were confirmed by means of IR, 1H NMR, MS and elemental analyses. The synthesized derivatives (5a-g,6a-g) wear subjected to the Microbiology Division, Microanalytical Center, Cairo University, (5a-g,6a-g) showed a variable degree of antimicrobial activity.

Suggested Citation

  • Sadek Abdou & Salah El-Qusy & Sami Ghabrial & Mahmoud Haggag, 2011. "Reactions with Visnaginone: Synthesis, Cyclisation and Microbial Evaluation of Some Visnaginone Thiosemicarbazone Derivatives," Modern Applied Science, Canadian Center of Science and Education, vol. 5(5), pages 140-140, October.
    • Handle: RePEc:ibn:masjnl:v:5:y:2011:i:5:p:140
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    JEL classification:

    • R00 - Urban, Rural, Regional, Real Estate, and Transportation Economics - - General - - - General
    • Z0 - Other Special Topics - - General

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