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In vitro Assessment of the Antioxidant Effect of Cunila microcephala Benth Infusion (Poejo) on Erythrocytes from Individuals with HIV/AIDS

Author

Listed:
  • Roberta Horn
  • Natacha Mori
  • Juliana de Oliveira
  • Paulo Moreira
  • Janaina Coser
  • Janice Zanella
  • Diego Golle
  • Gabriela Gelatti
  • Rodrigo Salazar

Abstract

The aim of the present study is to investigate in vitro antioxidant activity of Cunila microcephala Benth infusion (Poejo) in erythrocytes from individuals with HIV/AIDS. Erythrocytes were used from seventeen patients of both sexes, with HIV/AIDS, receiving antiretroviral therapy and the control group consisted of erythrocytes of HIV/AIDS free individuals belonging to both sexes. The erythrocytes were treated in vitro for an hour with infusions of Poejo at the following concentrations- 1, 5, 10, 25 and 50 g/L After treatment, the levels of thiobarbituric acid reactive substances (TBARS), carbonylated proteins (CPs), and reduced glutathione (GSH) were measured. A reduction in lipoperoxidation and protein carbonylation was observed after treatment with poejo tea at the concentrations of 5, 10, 25 and 50g/L. In addition, a reduction of GSH at such concentrations was observed. Poejo infusion appears to perform an antioxidant activity in lipid oxidation and in the protein carbonylation found in individuals with HIV/AIDS.

Suggested Citation

  • Roberta Horn & Natacha Mori & Juliana de Oliveira & Paulo Moreira & Janaina Coser & Janice Zanella & Diego Golle & Gabriela Gelatti & Rodrigo Salazar, 2017. "In vitro Assessment of the Antioxidant Effect of Cunila microcephala Benth Infusion (Poejo) on Erythrocytes from Individuals with HIV/AIDS," Journal of Agricultural Science, Canadian Center of Science and Education, vol. 9(7), pages 1-97, June.
    • Handle: RePEc:ibn:jasjnl:v:9:y:2017:i:7:p:97
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    JEL classification:

    • R00 - Urban, Rural, Regional, Real Estate, and Transportation Economics - - General - - - General
    • Z0 - Other Special Topics - - General

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