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Congenital and Blood Transfusion Transmission of Chagas Disease: A Framework Using Mathematical Modeling

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Listed:
  • Edneide Ramalho
  • Jones Albuquerque
  • Cláudio Cristino
  • Virginia Lorena
  • Jordi Gómez i Prat
  • Clara Prats
  • Daniel López

Abstract

Chagas disease or American trypanosomiasis is an important health problem in Latin America. Due to the mobility of Latin American population around the world, countries without vector presence started to report disease cases. We developed a deterministic compartmental model in order to gain insights into the disease dynamics in a scenario without vector presence, considering congenital transmission and transmission by blood transfusion. The model was used to evaluate the epidemiological effect of control measures. It was applied to demographic data from Spain and sensitivity analysis was performed on model parameters associated with control strategies.

Suggested Citation

  • Edneide Ramalho & Jones Albuquerque & Cláudio Cristino & Virginia Lorena & Jordi Gómez i Prat & Clara Prats & Daniel López, 2018. "Congenital and Blood Transfusion Transmission of Chagas Disease: A Framework Using Mathematical Modeling," Complexity, Hindawi, vol. 2018, pages 1-10, November.
    • Handle: RePEc:hin:complx:1589016
    DOI: 10.1155/2018/1589016
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    References listed on IDEAS

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    1. Ana Requena-Méndez & Edelweiss Aldasoro & Elisa de Lazzari & Elisa Sicuri & Michael Brown & David A J Moore & Joaquim Gascon & Jose Muñoz, 2015. "Prevalence of Chagas Disease in Latin-American Migrants Living in Europe: A Systematic Review and Meta-analysis," PLOS Neglected Tropical Diseases, Public Library of Science, vol. 9(2), pages 1-15, February.
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