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Itaconic Acid and Its Applications for Textile, Pharma and Agro-Industrial Purposes

Author

Listed:
  • Nisha Devi

    (School of Bioengineering and Food Technology, Shoolini University of Biotechnology and Management Sciences, Solan 173229, Himachal Pradesh, India)

  • Shubhangi Singh

    (School of Bioengineering and Food Technology, Shoolini University of Biotechnology and Management Sciences, Solan 173229, Himachal Pradesh, India)

  • Shivakumar Manickam

    (Petroleum and Chemical Engineering Department, Faculty of Engineering, University Teknologi Brunei, Bandar Seri Begawan BE1410, Brunei)

  • Natália Cruz-Martins

    (Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal
    Institute for Research and Innovation in Health (i3S), University of Porto, 4200-135 Porto, Portugal
    Institute of Research and Advanced, Training in Health Sciences and Technologies (CESPU), Rua Central de Gandra, 1317, 4585-116 Gandra, PRD, Portugal
    TOXRUN—Toxicology Research Unit, University Institute of Health Sciences, CESPU, 4585-116 Gandra, CRL, Portugal)

  • Vinod Kumar

    (School of Water, Energy and Environment, Cranfield University, Cranfield MK43 0KL, UK)

  • Rachna Verma

    (School of Biological and Environmental Sciences, Shoolini University of Biotechnology and Management Sciences, Solan 173229, Himachal Pradesh, India)

  • Dinesh Kumar

    (School of Bioengineering and Food Technology, Shoolini University of Biotechnology and Management Sciences, Solan 173229, Himachal Pradesh, India)

Abstract

Itaconic acid (IA) is a well-known bio-based monounsaturated organic acid (C 5 H 6 O 4 ), with a white color and crystalline structure. It is widely used in the agro-based, plastics, textile, paint and pharmaceutical sectors, owing to its flexible structure, due to the presence of functional groups with covalent double bonds. IA is an alternative to the petrochemicals acrylic and methacrylic acids. Commercial manufacturing of IA using Aspergillus terreus is more economically effective and feasible, and the Department of Energy (DOE) of the United States added IA under the “top 12” organic chemicals in 2004. This review provides an overview on the synthesis of IA and improvement of its yield by mutagenesis and metabolic engineering of Aspergillus and other fungal strains, along with its wide applications for food, pharmaceutical and textile purposes.

Suggested Citation

  • Nisha Devi & Shubhangi Singh & Shivakumar Manickam & Natália Cruz-Martins & Vinod Kumar & Rachna Verma & Dinesh Kumar, 2022. "Itaconic Acid and Its Applications for Textile, Pharma and Agro-Industrial Purposes," Sustainability, MDPI, vol. 14(21), pages 1-24, October.
    • Handle: RePEc:gam:jsusta:v:14:y:2022:i:21:p:13777-:d:951748
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    Cited by:

    1. Shashi Kant Bhatia, 2023. "Biorefinery for the Sustainable Biochemicals Production: Process Design and Technological Advances," Sustainability, MDPI, vol. 15(10), pages 1-3, May.

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