Deciphering the Efficacy of No-Attention Architectures in Computed Tomography Image Classification: A Paradigm Shift

The burgeoning domain of medical imaging has witnessed a paradigm shift with the integration of AI, particularly deep learning, enhancing diagnostic precision and expediting the analysis of Computed Tomography (CT) images. This study introduces an innovative Multilayer Perceptron-driven model, DiagnosticMLP, which sidesteps the computational intensity of attention-based mechanisms, favoring a no-attention architecture that leverages Fourier Transforms for global information capture and spatial gating units for local feature emphasis. This study’s methodology encompasses a sophisticated augmentation and patching strategy at the input level, followed by a series of MLP blocks designed to extract hierarchical features and spatial relationships, culminating in a global average pooling layer before classification. Evaluated against state-of-the-art MLP-based models including MLP-Mixer, FNet, gMLP, and ResMLP across diverse and extensive CT datasets, including abdominal, and chest scans, DiagnosticMLP demonstrated a remarkable ability to converge efficiently, with competitive accuracy, F1 scores, and AUC metrics. Notably, in datasets featuring kidney and abdomen disorders, the model showcased superior generalization capabilities, underpinned by its unique design that addresses the complexity inherent in CT imaging. The findings in terms of accuracy and precision-recall balance posit DiagnosticMLP as an exceptional outperforming alternative to attention-reliant models, paving the way for streamlined, efficient, and scalable AI tools in medical diagnostics, reinforcing the potential for AI-augmented precision medicine without the dependency on attention-based architectures.