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Association of the Joint Effect of Menopause and Hormone Replacement Therapy and Cancer in African American Women: The Jackson Heart Study

Author

Listed:
  • Brenda W. Campbell Jenkins

    (Jackson Heart Study Coordinating Center, Jackson State University, 350 West Woodrow Wilson Drive, Suite 701, Jackson, MS 39213, USA)

  • Clifton Addison

    (Jackson Heart Study Coordinating Center, Jackson State University, 350 West Woodrow Wilson Drive, Suite 701, Jackson, MS 39213, USA)

  • Gregory Wilson

    (Jackson Heart Study Coordinating Center, Jackson State University, 350 West Woodrow Wilson Drive, Suite 701, Jackson, MS 39213, USA)

  • Jiankang Liu

    (Jackson Heart Study, Department of Medicine, University of Mississippi Medical Center, 350 West Woodrow Wilson Drive, Suite 701, Jackson, MS 39213, USA)

  • Melody Fortune

    (Mississippi Department of Health, 570 East Woodrow Wilson, Jackson, MS 39213, USA)

  • Kiana Robinson

    (Jackson Heart Study Coordinating Center, Jackson State University, 350 West Woodrow Wilson Drive, Suite 701, Jackson, MS 39213, USA)

  • Monique White

    (Project Health, Jackson State University, 350 West Woodrow Wilson Drive, Suite 701, Jackson, MS 39213, USA)

  • Daniel Sarpong

    (Jackson Heart Study Coordinating Center, Jackson State University, 350 West Woodrow Wilson Drive, Suite 701, Jackson, MS 39213, USA)

Abstract

Cancer is the second leading cause of death in the US and in Mississippi. Breast cancer (BC) is the most common cancer among women, and the underlying pathophysiology remains unknown, especially among African American (AA) women. The study purpose was to examine the joint effect of menopause status (MS) and hormone replacement therapy (HRT) on the association with cancers, particularly BC using data from the Jackson Heart Study. The analytic sample consisted of 3202 women between 35 and 84 years of which 73.7% and 22.6% were postmenopausal and on HRT, respectively. There were a total of 190 prevalent cancer cases (5.9%) in the sample with 22.6% breast cancer cases. Menopause (p

Suggested Citation

  • Brenda W. Campbell Jenkins & Clifton Addison & Gregory Wilson & Jiankang Liu & Melody Fortune & Kiana Robinson & Monique White & Daniel Sarpong, 2011. "Association of the Joint Effect of Menopause and Hormone Replacement Therapy and Cancer in African American Women: The Jackson Heart Study," IJERPH, MDPI, vol. 8(6), pages 1-14, June.
    • Handle: RePEc:gam:jijerp:v:8:y:2011:i:6:p:2491-2504:d:12901
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