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Effect of Butachlor on Antioxidant Enzyme Status and Lipid Peroxidation in Fresh Water African Catfish, ( Clarias gariepinus )

Author

Listed:
  • E. O. Farombi

    (Drug Metabolism and Toxicology Research Laboratories, Department of Biochemistry College of Medicine, University of Ibadan, Nigeria)

  • Y. R. Ajimoko

    (Drug Metabolism and Toxicology Research Laboratories, Department of Biochemistry College of Medicine, University of Ibadan, Nigeria)

  • O. A. Adelowo

    (Drug Metabolism and Toxicology Research Laboratories, Department of Biochemistry College of Medicine, University of Ibadan, Nigeria)

Abstract

The present study was undertaken to evaluate the influence of butachlor, a widely used herbicide, on antioxidant enzyme system and lipid peroxidation formation in African cat fish ( Clarias gariepinus ). Fish were exposed to sub-lethal concentrations of butachlor 1, 2, 2.5 ppm and sacrificed 24hrs after treatment. A significant increase in malondialdehyde formation was observed in the liver, kidney, gills and heart of the fish following exposure to different concentrations of butachlor. Superoxide dismutase and catalase activities increased in the liver and kidney but decreased in the gills and heart in a concentration-dependent pattern. Glutathione level and glutathione-Stransferase activities increased (P

Suggested Citation

  • E. O. Farombi & Y. R. Ajimoko & O. A. Adelowo, 2008. "Effect of Butachlor on Antioxidant Enzyme Status and Lipid Peroxidation in Fresh Water African Catfish, ( Clarias gariepinus )," IJERPH, MDPI, vol. 5(5), pages 1-5, December.
    • Handle: RePEc:gam:jijerp:v:5:y:2008:i:5:p:423-427:d:3767
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    Cited by:

    1. Christopher Ddidigwu Nwani & Wazir Singh Lakra & Naresh Sahebrao Nagpure & Ravindra Kumar & Basdeo Kushwaha & Satish Kumar Srivastava, 2010. "Toxicity of the Herbicide Atrazine: Effects on Lipid Peroxidation and Activities of Antioxidant Enzymes in the Freshwater Fish Channa P unctatus (Bloch)," IJERPH, MDPI, vol. 7(8), pages 1-15, August.

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