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Exposure of Laboratory Mice to Domestic Cooking Gas: - Implications for Toxicity

Author

Listed:
  • Oyeronke A. Odunola

    (Cancer Research and Molecular Biology Laboratories, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan, Nigeria)

  • Emmanuel Uka

    (Cancer Research and Molecular Biology Laboratories, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan, Nigeria)

  • Kazeem A. Akinwumi

    (Cancer Research and Molecular Biology Laboratories, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan, Nigeria
    Department of Chemical Sciences, College of Natural and Applied Sciences, Bells University of Technology, Ota, Nigeria)

  • Michael A. Gbadegesin

    (Cancer Research and Molecular Biology Laboratories, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan, Nigeria)

  • Olabode O. Osifeso

    (Cancer Research and Molecular Biology Laboratories, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan, Nigeria)

  • Madu D. Ibegbu

    (Cancer Research and Molecular Biology Laboratories, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan, Nigeria
    Department of Medical Biochemistry, University of Nigeria, Enugu Campus, Enugu, Nigeria)

Abstract

The ability of domestic cooking gas to induce hepatotoxicity and clastogenicity in mice was studied. The mice were exposed to domestic gas for twenty-one days at doses of 100 mg/kg, 200 mg/kg and 300 mg/kg respectively. The positive control group of mice were given sodium arsenite intraperitoneously at a dose of 2.5mg/kg body weight. While the negative control group had only distilled water, sodium arsenite significantly (p

Suggested Citation

  • Oyeronke A. Odunola & Emmanuel Uka & Kazeem A. Akinwumi & Michael A. Gbadegesin & Olabode O. Osifeso & Madu D. Ibegbu, 2008. "Exposure of Laboratory Mice to Domestic Cooking Gas: - Implications for Toxicity," IJERPH, MDPI, vol. 5(3), pages 1-5, September.
    • Handle: RePEc:gam:jijerp:v:5:y:2008:i:3:p:172-176:d:2681
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