Author
Listed:
- Camila Miriam Suemi Sato Barros do Amaral
(Fundação de Medicina Tropical Dr Heitor Vieira Dourado, Manaus 69040-000, Brazil
Universidade do Estado do Amazonas, Manaus 69065-001, Brazil)
- Jefferson Valente
(Universidade do Estado do Amazonas, Manaus 69065-001, Brazil)
- Cássia da Luz Goulart
(Fundação de Medicina Tropical Dr Heitor Vieira Dourado, Manaus 69040-000, Brazil)
- Bernardo Maia da Silva
(Fundação de Medicina Tropical Dr Heitor Vieira Dourado, Manaus 69040-000, Brazil)
- Alexandre Silva Neto
(Fundação de Medicina Tropical Dr Heitor Vieira Dourado, Manaus 69040-000, Brazil)
- Nadia Cubas-Vega
(Universidad Nacional Autónoma de Honduras, Tegucigalpa 11101, Honduras)
- Anna Gabriela Rezende
(Universidade Federal do Amazonas, Manaus 69067-005, Brazil)
- Eduardo Fernandes
(Universidade do Estado do Amazonas, Manaus 69065-001, Brazil)
- Mayla Gabriela Silva Borba
(Universidade do Estado do Amazonas, Manaus 69065-001, Brazil
Hospital e Pronto-Socorro Delphina Rinaldi Abdel Aziz, Manaus 69093-415, Brazil)
- Vanderson Sampaio
(Instituto Todos pela Saúde, São Paulo 01310-942, Brazil)
- Wuelton Monteiro
(Fundação de Medicina Tropical Dr Heitor Vieira Dourado, Manaus 69040-000, Brazil
Universidade do Estado do Amazonas, Manaus 69065-001, Brazil)
- Gisely Cardoso de Melo
(Fundação de Medicina Tropical Dr Heitor Vieira Dourado, Manaus 69040-000, Brazil
Universidade do Estado do Amazonas, Manaus 69065-001, Brazil)
- Marcus Lacerda
(Fundação de Medicina Tropical Dr Heitor Vieira Dourado, Manaus 69040-000, Brazil
Universidade do Estado do Amazonas, Manaus 69065-001, Brazil
Instituto Todos pela Saúde, São Paulo 01310-942, Brazil
Instituto Leônidas & Maria Deane, Fundação Oswaldo Cruz (ILMD/Fiocruz Amazônia), Manaus 69057-070, Brazil)
- Guilherme Peixoto Tinoco Arêas
(Universidade Federal do Amazonas, Manaus 69067-005, Brazil)
- Fernando Almeida-Val
(Fundação de Medicina Tropical Dr Heitor Vieira Dourado, Manaus 69040-000, Brazil
Universidade do Estado do Amazonas, Manaus 69065-001, Brazil
Universidade Federal do Amazonas, Manaus 69067-005, Brazil
Fernando Fonseca de Almeida e Val, Fundação de Medicina Tropical Doutor Heitor Vieira Dourado, Av. Pedro Teixeira, 25 Bairro Dom Pedro, Manaus 69040-000, Brazil)
Abstract
Post-acute COVID-19 syndrome (PACS) is characterized by the persistence of one or more symptoms after the acute phase, leading to physical disabilities. This study aims to investigate whether the functional capacity and respiratory function 120 days post-COVID-19 differed according to the level of respiratory support needed during hospitalization in acute COVID-19 in the pre-vaccine rollout period. We followed up with 118 COVID-19 hospitalized patients in the acute phase until 120 days post-acute disease, with patients split into a Non-Invasive Oxygen Therapy Group (OTG, n = 72), Invasive Mechanical Ventilation Group (IMV, n = 12), and Room Air Group (RAG, n = 34), assessing the body composition, respiratory muscle strength, pulmonary function, functional capacity, and muscle strength at the follow-up visit. In total, 54 individuals (45.8%) were female, with a median age of 48 years old (IQR: 41–58). We found that the group with IMV was older ( p < 0.001), had more admissions to the ICU ( p < 0.001), and had longer hospital stays ( p < 0.001). There were no statistically significant differences between groups (OTG, IMV, and RAG) for the spirometry function ( p = 0.31), DASI score ( p = 0.77), manovacuometry (MIP p = 0.74; MEP p = 0.23), 6MWT ( p = 0.43), and handgrip ( p = 0.19) outcomes. At D120, the IMV group had an important loss of body muscle mass (BMM) and a higher BMM than RAG ( p = 0.02). Reduction in MIP ( p = 0.01) and MEP ( p = 0.02) in the IMV group and OTG group when compared to the RAG was also observed. Functional outcomes at 120 days from COVID-19 hospitalization were not found to be associated with the levels of oxygen supplementation during acute disease in this group of participants.
Suggested Citation
Camila Miriam Suemi Sato Barros do Amaral & Jefferson Valente & Cássia da Luz Goulart & Bernardo Maia da Silva & Alexandre Silva Neto & Nadia Cubas-Vega & Anna Gabriela Rezende & Eduardo Fernandes & M, 2024.
"Impact of Respiratory Support During Hospitalization on Functional Outcomes in Long COVID: A Post-Hoc Analysis of a Prospective Cohort Study,"
IJERPH, MDPI, vol. 22(1), pages 1-11, December.
Handle:
RePEc:gam:jijerp:v:22:y:2024:i:1:p:49-:d:1558035
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