Author
Listed:
- Alina Schenk
(The Doctoral School, George Emil Palade University of Medicine, Pharmacy, Science and Technology, 540142 Targu Mures, Romania)
- Cosmin Octavian Popa
(Department of Ethics and Social Science, George Emil Palade University of Medicine, Pharmacy, Science and Technology, 540142 Targu Mures, Romania)
- Cristiana Manuela Cojocaru
(The Doctoral School, George Emil Palade University of Medicine, Pharmacy, Science and Technology, 540142 Targu Mures, Romania)
- Ștefan Marian
(Department of Psychology, West University of Timişoara, 4 Vasile Pâvan Boulevard, 300223 Timişoara, Romania)
- Smaranda Maier
(Neurology Clinic I, Emergency Clinical County Hospital, 540163 Targu Mures, Romania
Department of Neurology, George Emil Palade University of Medicine, Pharmacy, Science and Technology, 540142 Targu Mures, Romania)
- Rodica Bălașa
(Neurology Clinic I, Emergency Clinical County Hospital, 540163 Targu Mures, Romania
Department of Neurology, George Emil Palade University of Medicine, Pharmacy, Science and Technology, 540142 Targu Mures, Romania)
Abstract
Background: Left undiagnosed and untreated, the association between multiple sclerosis and mental health difficulties significantly increases the multimorbidity risk in these patients. Hence, the purpose of this systematic review and meta-analysis was to estimate the prevalence of neuroticism, depression, and anxiety in MS and to explore the cumulative impact of these psychological factors on the disease expression. Methods: A literature search was conducted on PubMed, Web of Science, Scopus, and Google Scholar databases, according to the PRISMA guidelines. Also, the potential risk of bias was assessed using the AXIS tool. Result: After a rigorous full-text examination, among the 756 identified studies, 22 investigations were considered for the systematic review, and 10 studies were selected for the meta-analysis. The prevalence of neuroticism in the studied population was 24.06% (95% CI: 16.79–33.34), of depression 20.77% (95% CI: 7.67–33.88), while the presence of anxiety was found in 23.94% (95% CI: 6.21–40.36). Conclusions: The main finding of this research confirms that psychiatric disorders often co-occur with MS, impacting the clinical symptoms and life quality of patients living with this illness. For a better understanding of the interaction between personality, depression, anxiety, and the disease symptoms, future research should consider conducting comparisons on more homogenous studies.
Suggested Citation
Alina Schenk & Cosmin Octavian Popa & Cristiana Manuela Cojocaru & Ștefan Marian & Smaranda Maier & Rodica Bălașa, 2024.
"Neuroticism as a Common Factor in Depression and Anxiety Associated with Multiple Sclerosis—A Systematic Review and Meta-Analysis,"
IJERPH, MDPI, vol. 21(10), pages 1-12, September.
Handle:
RePEc:gam:jijerp:v:21:y:2024:i:10:p:1264-:d:1484582
Download full text from publisher
Corrections
All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:21:y:2024:i:10:p:1264-:d:1484582. See general information about how to correct material in RePEc.
If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.
We have no bibliographic references for this item. You can help adding them by using this form .
If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.
For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .
Please note that corrections may take a couple of weeks to filter through
the various RePEc services.