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Evaluating Processing Speed and Reaction Time Outcome Measures in Children and Adolescents with Down Syndrome

Author

Listed:
  • Emily K. Schworer

    (Division of Developmental and Behavioral Pediatrics, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229, USA
    Waisman Center, University of Wisconsin-Madison, Madison, WI 53705, USA)

  • Mekibib Altaye

    (Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
    Division of Biostatistics and Epidemiology, Cincinnati Children’s Hospital, Cincinnati, OH 45229, USA)

  • Deborah J. Fidler

    (Human Development and Family Studies, Colorado State University, Fort Collins, CO 80523, USA)

  • Dean W. Beebe

    (Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
    Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229, USA)

  • Susan Wiley

    (Division of Developmental and Behavioral Pediatrics, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229, USA
    Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA)

  • Emily K. Hoffman

    (Division of Developmental and Behavioral Pediatrics, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229, USA)

  • Anna J. Esbensen

    (Division of Developmental and Behavioral Pediatrics, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229, USA
    Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA)

Abstract

Reliable and valid cognitive outcome measures, including examiner-administered and computer-facilitated assessments of processing speed and reaction time, are necessary for future clinical trials that include individuals with Down syndrome (DS). The current study evaluated the score distributions and psychometric properties of four examiner-administered and three computerized processing speed and reaction time measures. Participants included 97 individuals with DS, aged 6 to 17 (M = 12.6, SD = 3.3). Two examiner-administered measures (Differential Ability Scales-II Rapid Naming and Cat/dog Stroop Congruent) met most predetermined psychometric criteria. Other assessments demonstrated good test-retest reliability and had negligible practice effects but lacked adequate feasibility. Recommendations for using processing speed and reaction time assessments in research and suggestions for modifications of measures are discussed.

Suggested Citation

  • Emily K. Schworer & Mekibib Altaye & Deborah J. Fidler & Dean W. Beebe & Susan Wiley & Emily K. Hoffman & Anna J. Esbensen, 2023. "Evaluating Processing Speed and Reaction Time Outcome Measures in Children and Adolescents with Down Syndrome," IJERPH, MDPI, vol. 20(6), pages 1-15, March.
    • Handle: RePEc:gam:jijerp:v:20:y:2023:i:6:p:5202-:d:1098384
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