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Case Report: Acute Intoxication from Phosphine Inhalation

Author

Listed:
  • Longke Shi

    (School of Public Health, Shandong University, Jinan 250012, China
    Department of Poisoning and Occupational Diseases, Emergency Medicine, Qilu Hospital of Shandong University, Jinan 250012, China)

  • Tianzi Jian

    (Department of Poisoning and Occupational Diseases, Emergency Medicine, Qilu Hospital of Shandong University, Jinan 250012, China)

  • Yiming Tao

    (Department of Poisoning and Occupational Diseases, Emergency Medicine, Qilu Hospital of Shandong University, Jinan 250012, China)

  • Yaqian Li

    (Department of Poisoning and Occupational Diseases, Emergency Medicine, Qilu Hospital of Shandong University, Jinan 250012, China)

  • Guangcai Yu

    (Department of Poisoning and Occupational Diseases, Emergency Medicine, Qilu Hospital of Shandong University, Jinan 250012, China)

  • Liwen Zhao

    (School of Public Health, Shandong University, Jinan 250012, China
    Department of Poisoning and Occupational Diseases, Emergency Medicine, Qilu Hospital of Shandong University, Jinan 250012, China)

  • Zixin Wen

    (School of Nursing and Rehabilitation, Cheeloo College of Medicine, Shandong University, Jinan 250012, China)

  • Baotian Kan

    (School of Nursing and Rehabilitation, Cheeloo College of Medicine, Shandong University, Jinan 250012, China
    Department of Geriatric Medicine, Department of Nursing, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan 250012, China)

  • Xiangdong Jian

    (School of Public Health, Shandong University, Jinan 250012, China
    Department of Poisoning and Occupational Diseases, Emergency Medicine, Qilu Hospital of Shandong University, Jinan 250012, China)

Abstract

Aluminum phosphide is a highly effective insecticide for fumigation in granaries and is often used in rural grain storage. However, people’s awareness of its toxicity is not strong. A case of acute inhalation toxicity of phosphine caused by the use of aluminum phosphide to fumigate a granary is reported here. The case presented with aspiration pneumonia and acute left heart failure. The patient was cured using comprehensive life support treatment, including respiratory support, antiarrhythmic treatment, and blood pressure maintenance with vasoactive drugs. There is no specific antidote for phosphine poisoning at present, and the comprehensive application of restricted fluid resuscitation, high-dose glucocorticoid shock, vasoactive drugs and bedside hemofiltration is significant in improving the prognosis of patients. It is also important to remind people to pay attention to their own protection in the process of using aluminum phosphide.

Suggested Citation

  • Longke Shi & Tianzi Jian & Yiming Tao & Yaqian Li & Guangcai Yu & Liwen Zhao & Zixin Wen & Baotian Kan & Xiangdong Jian, 2023. "Case Report: Acute Intoxication from Phosphine Inhalation," IJERPH, MDPI, vol. 20(6), pages 1-7, March.
    • Handle: RePEc:gam:jijerp:v:20:y:2023:i:6:p:5021-:d:1095168
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