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Risk Factors for Mortality of Hospitalized Adult Patients with COVID-19 Pneumonia: A Two-Year Cohort Study in a Private Tertiary Care Center in Mexico

Author

Listed:
  • Carlos Axel López-Pérez

    (Escuela de Medicina y Ciencias de la Salud, Tecnologico de Monterrey, Zapopan 45201, Mexico)

  • Francisco J. Santa Cruz-Pavlovich

    (Escuela de Medicina y Ciencias de la Salud, Tecnologico de Monterrey, Zapopan 45201, Mexico)

  • Juan Eduardo Montiel-Cortés

    (Departamento de Medicina Interna, Hospital San Javier, Guadalajara 44670, Mexico
    Centro Universitario de Ciencias de la Salud (CUCS), Universidad de Guadalajara, Zapopan 44340, Mexico)

  • Adriana Núñez-Muratalla

    (Departamento de Medicina Interna, Hospital San Javier, Guadalajara 44670, Mexico
    Facultad de Medicina, Universidad Autónoma de Guadalajara, Zapopan 45129, Mexico)

  • Ruth Bibani Morán-González

    (Escuela de Medicina y Ciencias de la Salud, Tecnologico de Monterrey, Zapopan 45201, Mexico)

  • Ricardo Villanueva-Gaona

    (Escuela de Medicina y Ciencias de la Salud, Tecnologico de Monterrey, Zapopan 45201, Mexico)

  • Xochitl Franco-Mojica

    (Escuela de Medicina y Ciencias de la Salud, Tecnologico de Monterrey, Zapopan 45201, Mexico)

  • Denisse Gabriela Moreno-Sandoval

    (Escuela de Medicina y Ciencias de la Salud, Tecnologico de Monterrey, Zapopan 45201, Mexico)

  • Joselyn Anacaren González-Bañuelos

    (Escuela de Medicina y Ciencias de la Salud, Tecnologico de Monterrey, Zapopan 45201, Mexico)

  • Alan Ulises López-Pérez

    (Escuela de Medicina y Ciencias de la Salud, Tecnologico de Monterrey, Zapopan 45201, Mexico)

  • Marily Flores-González

    (Departamento de Medicina Interna, Hospital San Javier, Guadalajara 44670, Mexico
    Facultad de Medicina, Universidad Autónoma de Guadalajara, Zapopan 45129, Mexico)

  • Cristina Grijalva-Ruiz

    (Departamento de Medicina Interna, Hospital San Javier, Guadalajara 44670, Mexico
    Facultad de Medicina, Universidad Autónoma de Guadalajara, Zapopan 45129, Mexico)

  • Edna Daniela Valdez-Mendoza

    (Departamento de Medicina Interna, Hospital San Javier, Guadalajara 44670, Mexico
    Facultad de Medicina, Universidad Autónoma de Guadalajara, Zapopan 45129, Mexico)

  • Luis Renee González-Lucano

    (Escuela de Medicina y Ciencias de la Salud, Tecnologico de Monterrey, Zapopan 45201, Mexico)

  • Martín López-Zendejas

    (Escuela de Medicina y Ciencias de la Salud, Tecnologico de Monterrey, Zapopan 45201, Mexico
    Departamento de Medicina Interna, Hospital San Javier, Guadalajara 44670, Mexico)

Abstract

During the COVID-19 pandemic, the high prevalence of comorbidities and the disparities between the public and private health subsystems in Mexico substantially contributed to the severe impact of the disease. The objective of this study was to evaluate and compare the risk factors at admission for in-hospital mortality of patients with COVID-19. A 2-year retrospective cohort study of hospitalized adult patients with COVID-19 pneumonia was conducted at a private tertiary care center. The study population consisted of 1258 patients with a median age of 56 ± 16.5 years, of whom 1093 recovered (86.8%) and 165 died (13.1%). In the univariate analysis, older age ( p < 0.001), comorbidities such as hypertension ( p < 0.001) and diabetes ( p < 0.001), signs and symptoms of respiratory distress, and markers of acute inflammatory response were significantly more frequent in non-survivors. The multivariate analysis showed that older age ( p < 0.001), the presence of cyanosis ( p = 0.005), and previous myocardial infarction ( p = 0.032) were independent predictors of mortality. In the studied cohort, the risk factors present at admission associated with increased mortality were older age, cyanosis, and a previous myocardial infarction, which can be used as valuable predictors for patients’ outcomes. To our knowledge, this is the first study analyzing predictors of mortality in COVID-19 patients attended in a private tertiary hospital in Mexico.

Suggested Citation

  • Carlos Axel López-Pérez & Francisco J. Santa Cruz-Pavlovich & Juan Eduardo Montiel-Cortés & Adriana Núñez-Muratalla & Ruth Bibani Morán-González & Ricardo Villanueva-Gaona & Xochitl Franco-Mojica & De, 2023. "Risk Factors for Mortality of Hospitalized Adult Patients with COVID-19 Pneumonia: A Two-Year Cohort Study in a Private Tertiary Care Center in Mexico," IJERPH, MDPI, vol. 20(5), pages 1-14, March.
    • Handle: RePEc:gam:jijerp:v:20:y:2023:i:5:p:4450-:d:1085533
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    References listed on IDEAS

    as
    1. -, 2020. "Health and the economy: A convergence needed to address COVID-19 and retake the path of sustainable development in Latin America and the Caribbean," Libros y Documentos Institucionales, Naciones Unidas Comisión Económica para América Latina y el Caribe (CEPAL), number 45841 edited by Eclac.
    2. -, 2020. "Health and the economy: A convergence needed to address COVID-19 and retake the path of sustainable development in Latin America and the Caribbean," Coediciones, Naciones Unidas Comisión Económica para América Latina y el Caribe (CEPAL), number 45841 edited by Eclac.
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    Keywords

    COVID-19; cohort; mortality; Mexico;
    All these keywords.

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