IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v20y2023i4p3226-d1066162.html
   My bibliography  Save this article

Effect of Non-Pharmacological Methods in the Reduction of Neonatal Pain: Systematic Review and Meta-Analysis

Author

Listed:
  • Inmaculada García-Valdivieso

    (General Hospital Mancha Centre (HGMC), Castilla-La Mancha Health Service (SESCAM), 13600 Alcázar de San Juan, Spain)

  • Benito Yáñez-Araque

    (Department of Physical Activity and Sports Sciences, University of Castilla-La Mancha, Toledo Campus, 45071 Toledo, Spain)

  • Eva Moncunill-Martínez

    (Toledo University Hospital (HUT), Neonatal and Pediatric Oncology, Castilla-La Mancha Health Service (SESCAM), Theoretical Collaborator University of Castilla-La Mancha, Toledo Campus, 45071 Toledo, Spain)

  • M. Jesús Bocos-Reglero

    (National Hospital of Paraplegics (HNP), Castilla-La Mancha Health Service (SESCAM), Theoretical Collaborator University of Castilla-La Mancha, Toledo Campus, 45071 Toledo, Spain)

  • Sagrario Gómez-Cantarino

    (Faculty of Physiotherapy and Nursing, University of Castilla-La Mancha, Toledo Campus, 45071 Toledo, Spain)

Abstract

In neonatology, neonates have traditionally been considered incapable of feeling pain, due to the immaturity of their nervous system. Currently, there is sufficient information on the perception of pain in neonates; however, this treatment at this crucial stage for development requires a better approach. For this reason, the aim of this study was to analyse the efficacy of non-pharmacological analgesia interventions during heel prick, and to assess their effects on heart rate (HR), premature infant pain profile (PIPP) and O 2 saturation. A systematic review and meta-analysis was performed following the guidelines of the preferred reporting items for systematic reviews and meta-analyses (PRISMA), and the Cochrane collaboration handbook. The databases PubMed, Cochrane Library, Web of Science, Scopus, CINAHL and Science Direct were searched until the end of January 2022. The DerSimonian and Laird methods were used to estimate the effect size with a 95% confidence interval (CI95%). Effect size estimates were 0.05 (95% CI: −0.19, 0.29) for HR, −0.02 (95% CI: −0.24, 0.21) for PIPP scale, and −0.12 (95% CI: −0.29, 0.05) for O 2 saturation. The non-pharmacological interventions analysed (breastfeeding, kangaroo-mother care method, oral sucrose and non-nutritive sucking) were not statistically significant in reducing neonatal pain, but did influence the decrease in pain score and a faster stabilisation of vital signs.

Suggested Citation

  • Inmaculada García-Valdivieso & Benito Yáñez-Araque & Eva Moncunill-Martínez & M. Jesús Bocos-Reglero & Sagrario Gómez-Cantarino, 2023. "Effect of Non-Pharmacological Methods in the Reduction of Neonatal Pain: Systematic Review and Meta-Analysis," IJERPH, MDPI, vol. 20(4), pages 1-14, February.
    • Handle: RePEc:gam:jijerp:v:20:y:2023:i:4:p:3226-:d:1066162
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/20/4/3226/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/20/4/3226/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Hsiang-Yun Lan & Luke Yang & Chiao-Hsuan Lin & Kao-Hsian Hsieh & Yue-Cune Chang & Ti Yin, 2021. "Breastmilk as a Multisensory Intervention for Relieving Pain during Newborn Screening Procedures: A Randomized Control Trial," IJERPH, MDPI, vol. 18(24), pages 1-10, December.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.

      Corrections

      All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:20:y:2023:i:4:p:3226-:d:1066162. See general information about how to correct material in RePEc.

      If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

      If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

      If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

      For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

      Please note that corrections may take a couple of weeks to filter through the various RePEc services.

      IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.