IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v20y2023i3p2403-d1050686.html
   My bibliography  Save this article

Adherence to Mediterranean Diet and Risk of Pancreatic Cancer: Systematic Review and Meta-Analysis

Author

Listed:
  • Daniele Nucci

    (Nutritional Support Unit, Veneto Institute of Oncology IOV-IRCCS, Via Gattamelata 64, 35128 Padua, Italy)

  • Mariateresa Nardi

    (Nutritional Support Unit, Veneto Institute of Oncology IOV-IRCCS, Via Gattamelata 64, 35128 Padua, Italy)

  • Andrea Cinnirella

    (Department of Biomedical Sciences for Health, University of Milan, Via Pascal, 20133 Milan, Italy)

  • Emanuela Campagnoli

    (Department of Biomedical Sciences for Health, University of Milan, Via Pascal, 20133 Milan, Italy)

  • Manuel Maffeo

    (Department of Biomedical Sciences for Health, University of Milan, Via Pascal, 20133 Milan, Italy)

  • Pier Mario Perrone

    (Department of Biomedical Sciences for Health, University of Milan, Via Pascal, 20133 Milan, Italy)

  • Viktoriia Shishmintseva

    (Department of Biomedical Sciences for Health, University of Milan, Via Pascal, 20133 Milan, Italy)

  • Francesca Maria Grosso

    (Department of Biomedical Sciences for Health, University of Milan, Via Pascal, 20133 Milan, Italy)

  • Ambra Castrofino

    (Department of Biomedical Sciences for Health, University of Milan, Via Pascal, 20133 Milan, Italy)

  • Silvana Castaldi

    (Department of Biomedical Sciences for Health, University of Milan, Via Pascal, 20133 Milan, Italy
    Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Via Francesco Sforza 35, 20122 Milan, Italy)

  • Luisa Romanò

    (Department of Biomedical Sciences for Health, University of Milan, Via Pascal, 20133 Milan, Italy)

  • Vincenza Gianfredi

    (Department of Biomedical Sciences for Health, University of Milan, Via Pascal, 20133 Milan, Italy)

Abstract

Pancreatic cancer (PC) represents the 6th cause of cancer death. Although the aetiology of PC is not completely understood, numerous risk factors have been identified in association with this cancer, among them diet. However, little is known about the association between the Mediterranean Diet (MedDiet) and the risk of PC. For this reason, we conducted a systematic review with meta-analysis according to the PRISMA guidelines, searching on three databases (PubMed/MEDLINE, Scopus, and EMBASE). The protocol was registered in PROSPERO. Both fixed and random effect models were performed. The Effect size was reported as a hazard ratio (HR) with a 95% Confidence Interval (CI). A total of eight articles were included. The methodological quality of the included meta-analyses was high. Our results show that a higher adherence to the MedDiet is associated with a lower risk of PC [HR:0.82 (0.76–0.88) p < 0.001, based on 1,301,320 subjects]. The results were also confirmed in sensitivity and subgroups analyses (avoidance of potential overlapping effects, type of tools used to assess dietary intake and the diagnosis of PC, prevalence and incidence of PC risk, country where the studies took place, sex, and cancer site). Promoting a higher adherence to the MedDiet could be an effective approach to reduce the risk of PC.

Suggested Citation

  • Daniele Nucci & Mariateresa Nardi & Andrea Cinnirella & Emanuela Campagnoli & Manuel Maffeo & Pier Mario Perrone & Viktoriia Shishmintseva & Francesca Maria Grosso & Ambra Castrofino & Silvana Castald, 2023. "Adherence to Mediterranean Diet and Risk of Pancreatic Cancer: Systematic Review and Meta-Analysis," IJERPH, MDPI, vol. 20(3), pages 1-24, January.
    • Handle: RePEc:gam:jijerp:v:20:y:2023:i:3:p:2403-:d:1050686
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/20/3/2403/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/20/3/2403/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Daniele Nucci & Cristina Fatigoni & Tania Salvatori & Mariateresa Nardi & Stefano Realdon & Vincenza Gianfredi, 2021. "Association between Dietary Fibre Intake and Colorectal Adenoma: A Systematic Review and Meta-Analysis," IJERPH, MDPI, vol. 18(8), pages 1-23, April.
    2. Daniele Nucci & Cristina Fatigoni & Andrea Amerio & Anna Odone & Vincenza Gianfredi, 2020. "Red and Processed Meat Consumption and Risk of Depression: A Systematic Review and Meta-Analysis," IJERPH, MDPI, vol. 17(18), pages 1-20, September.
    3. Vincenza Gianfredi & Maddalena Buffoli & Andrea Rebecchi & Roberto Croci & Aurea Oradini-Alacreu & Giuseppe Stirparo & Alessio Marino & Anna Odone & Stefano Capolongo & Carlo Signorelli, 2021. "Association between Urban Greenspace and Health: A Systematic Review of Literature," IJERPH, MDPI, vol. 18(10), pages 1-23, May.
    4. Daniele Nucci & Omar Enzo Santangelo & Sandro Provenzano & Cristina Fatigoni & Mariateresa Nardi & Pietro Ferrara & Vincenza Gianfredi, 2021. "Dietary Fiber Intake and Risk of Pancreatic Cancer: Systematic Review and Meta-Analysis of Observational Studies," IJERPH, MDPI, vol. 18(21), pages 1-20, November.
    5. Vincenza Gianfredi & Pietro Ferrara & Monica Dinu & Mariateresa Nardi & Daniele Nucci, 2022. "Diets, Dietary Patterns, Single Foods and Pancreatic Cancer Risk: An Umbrella Review of Meta-Analyses," IJERPH, MDPI, vol. 19(22), pages 1-19, November.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Daniele Nucci & Omar Enzo Santangelo & Sandro Provenzano & Mariateresa Nardi & Alberto Firenze & Vincenza Gianfredi, 2022. "Altered Food Behavior and Cancer: A Systematic Review of the Literature," IJERPH, MDPI, vol. 19(16), pages 1-15, August.
    2. Daniele Nucci & Vincenza Gianfredi & Pietro Ferrara & Omar Enzo Santangelo & Beatrice Varotto & Alessandra Feltrin & Antonella Galiano & Mariateresa Nardi, 2023. "Association between Malnutrition and Depression in Patients with Cancer: The Importance of Nutritional Status Evaluation in Cancer Care," IJERPH, MDPI, vol. 20(3), pages 1-10, January.
    3. Daniele Nucci & Omar Enzo Santangelo & Sandro Provenzano & Cristina Fatigoni & Mariateresa Nardi & Pietro Ferrara & Vincenza Gianfredi, 2021. "Dietary Fiber Intake and Risk of Pancreatic Cancer: Systematic Review and Meta-Analysis of Observational Studies," IJERPH, MDPI, vol. 18(21), pages 1-20, November.
    4. Vincenza Gianfredi & Pietro Ferrara & Flavia Pennisi & Giulia Casu & Andrea Amerio & Anna Odone & Daniele Nucci & Monica Dinu, 2022. "Association between Daily Pattern of Physical Activity and Depression: A Systematic Review," IJERPH, MDPI, vol. 19(11), pages 1-12, May.
    5. Daniela D’Alessandro & Andrea Rebecchi & Letizia Appolloni & Andrea Brambilla & Silvio Brusaferro & Maddalena Buffoli & Maurizio Carta & Alessandra Casuccio & Liliana Coppola & Maria Vittoria Corazza , 2023. "Re-Thinking the Environment, Cities, and Living Spaces for Public Health Purposes, According with the COVID-19 Lesson: The LVII Erice Charter," Land, MDPI, vol. 12(10), pages 1-17, September.
    6. Lisa Dandolo & Christina Hartig & Klaus Telkmann & Sophie Horstmann & Lars Schwettmann & Peter Selsam & Alexandra Schneider & Gabriele Bolte & on behalf of the INGER Study Group, 2022. "Decision Tree Analyses to Explore the Relevance of Multiple Sex/Gender Dimensions for the Exposure to Green Spaces: Results from the KORA INGER Study," IJERPH, MDPI, vol. 19(12), pages 1-25, June.
    7. Maddalena Buffoli & Silvia Mangili & Stefano Capolongo & Andrea Brambilla, 2022. "Explorative Study on Urban Public Space Renovation during COVID-19: Test of a Visual Web-Based Survey about the City of Saint German en Laye, France," Sustainability, MDPI, vol. 14(19), pages 1-17, September.
    8. Jeffrey Wilson & Xiao Xiao, 2023. "The Economic Value of Health Benefits Associated with Urban Park Investment," IJERPH, MDPI, vol. 20(6), pages 1-13, March.
    9. Levi N. Bonnell & Benjamin Littenberg, 2022. "Nonlinear Relationships among the Natural Environment, Health, and Sociodemographic Characteristics across US Counties," IJERPH, MDPI, vol. 19(11), pages 1-10, June.
    10. Kimon Krenz & Ashley Dhanani & Rosemary R. C. McEachan & Kuldeep Sohal & John Wright & Laura Vaughan, 2023. "Linking the Urban Environment and Health: An Innovative Methodology for Measuring Individual-Level Environmental Exposures," IJERPH, MDPI, vol. 20(3), pages 1-22, January.
    11. David Victorson & Gretchen Doninger & Scott Victorson & Gwen Victorson & Lars Hall & Carly Maletich & Bradley R. Corr & Kathy Scortino & Zachary Burns & Lori Allen & Ian Rosa & Kelley Quirk & Adekunle, 2021. "Psychosocial and Biological Outcomes of Immersive, Mindfulness-Based Treks in Nature for Groups of Young Adults and Caregivers Affected by Cancer: Results from a Single Arm Program Evaluation from 201," IJERPH, MDPI, vol. 18(23), pages 1-16, November.
    12. Hania M. Taha & Alexander N. Slade & Betty Schwartz & Anna E. Arthur, 2022. "A Case–Control Study Examining the Association of Fiber, Fruit, and Vegetable Intake and the Risk of Colorectal Cancer in a Palestinian Population," IJERPH, MDPI, vol. 19(12), pages 1-11, June.
    13. Doo-San Kim & Byeong-Cheol Lee & Kwang-Hi Park, 2021. "Determination of Motivating Factors of Urban Forest Visitors through Latent Dirichlet Allocation Topic Modeling," IJERPH, MDPI, vol. 18(18), pages 1-14, September.
    14. Vincenza Gianfredi & Pietro Ferrara & Monica Dinu & Mariateresa Nardi & Daniele Nucci, 2022. "Diets, Dietary Patterns, Single Foods and Pancreatic Cancer Risk: An Umbrella Review of Meta-Analyses," IJERPH, MDPI, vol. 19(22), pages 1-19, November.
    15. Lijuan Xu & Yan Lou & Caifu Li & Xuemei Tao & Maria Engström, 2022. "Person-Centered Climate, Garden Greenery and Well-Being among Nursing Home Residents: A Cross-Sectional Study," IJERPH, MDPI, vol. 20(1), pages 1-12, December.
    16. Jean C. Bikomeye & Andreas M. Beyer & Jamila L. Kwarteng & Kirsten M. M. Beyer, 2022. "Greenspace, Inflammation, Cardiovascular Health, and Cancer: A Review and Conceptual Framework for Greenspace in Cardio-Oncology Research," IJERPH, MDPI, vol. 19(4), pages 1-22, February.
    17. Hayley Walsh & Megan Lee & Talitha Best, 2023. "The Association between Vegan, Vegetarian, and Omnivore Diet Quality and Depressive Symptoms in Adults: A Cross-Sectional Study," IJERPH, MDPI, vol. 20(4), pages 1-12, February.
    18. Argyro Anna Kanelli & Maria Lydia Vardaka & Chrisovaladis Malesios & Zainab Jamidu Katima & Olga-Ioanna Kalantzi, 2024. "Can Campus Green Spaces Be Restorative? A Case Study from Tanzania," Sustainability, MDPI, vol. 16(3), pages 1-21, January.
    19. Tianrong Xu & Nikmatul Adha Nordin & Ainoriza Mohd Aini, 2022. "Urban Green Space and Subjective Well-Being of Older People: A Systematic Literature Review," IJERPH, MDPI, vol. 19(21), pages 1-29, October.
    20. Kristoffer Mattisson & Anna Axmon & Gunilla Carlsson & Agneta Malmgren Fänge & Connie Lethin & Emilie Stroh, 2022. "Sociodemographic Variations in the Availability of Urban Green Spaces in an Older Swedish Population," IJERPH, MDPI, vol. 19(19), pages 1-17, October.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:20:y:2023:i:3:p:2403-:d:1050686. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.