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Preoperative Risk Factors for Conversion from Laparoscopic to Open Cholecystectomy: A Systematic Review and Meta-Analysis

Author

Listed:
  • Roberta Magnano San Lio

    (Department of Medical and Surgical Sciences and Advanced Technologies “GF Ingrassia”, University of Catania, 95123 Catania, Italy)

  • Martina Barchitta

    (Department of Medical and Surgical Sciences and Advanced Technologies “GF Ingrassia”, University of Catania, 95123 Catania, Italy)

  • Andrea Maugeri

    (Department of Medical and Surgical Sciences and Advanced Technologies “GF Ingrassia”, University of Catania, 95123 Catania, Italy)

  • Serafino Quartarone

    (Department of General Surgery and Medical-Surgical Specialties, University of Catania, 95123 Catania, Italy)

  • Guido Basile

    (Department of General Surgery and Medical-Surgical Specialties, University of Catania, 95123 Catania, Italy)

  • Antonella Agodi

    (Department of Medical and Surgical Sciences and Advanced Technologies “GF Ingrassia”, University of Catania, 95123 Catania, Italy)

Abstract

Laparoscopic cholecystectomy is a standard treatment for patients with gallstones in the gallbladder. However, multiple risk factors affect the probability of conversion from laparoscopic cholecystectomy to open surgery. A greater understanding of the preoperative factors related to conversion is crucial to improve patient safety. In the present systematic review, we summarized the current knowledge about the main factors associated with conversion. Next, we carried out several meta-analyses to evaluate the impact of independent clinical risk factors on conversion rate. Male gender (OR = 1.907; 95%CI = 1.254–2.901), age > 60 years (OR = 4.324; 95%CI = 3.396–5.506), acute cholecystitis (OR = 5.475; 95%CI = 2.959–10.130), diabetes (OR = 2.576; 95%CI = 1.687–3.934), hypertension (OR = 1.931; 95%CI = 1.018–3.662), heart diseases (OR = 2.947; 95%CI = 1.047–8.296), obesity (OR = 2.228; 95%CI = 1.162–4.271), and previous upper abdominal surgery (OR = 3.301; 95%CI = 1.965–5.543) increased the probability of conversion. Our analysis of clinical factors suggested the presence of different preoperative conditions, which are non-modifiable but could be useful for planning the surgical scenario and improving the post-operatory phase.

Suggested Citation

  • Roberta Magnano San Lio & Martina Barchitta & Andrea Maugeri & Serafino Quartarone & Guido Basile & Antonella Agodi, 2022. "Preoperative Risk Factors for Conversion from Laparoscopic to Open Cholecystectomy: A Systematic Review and Meta-Analysis," IJERPH, MDPI, vol. 20(1), pages 1-15, December.
    • Handle: RePEc:gam:jijerp:v:20:y:2022:i:1:p:408-:d:1016131
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    References listed on IDEAS

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    1. Łukasz Warchałowski & Edyta Łuszczki & Anna Bartosiewicz & Katarzyna Dereń & Marta Warchałowska & Łukasz Oleksy & Artur Stolarczyk & Robert Podlasek, 2020. "The Analysis of Risk Factors in the Conversion from Laparoscopic to Open Cholecystectomy," IJERPH, MDPI, vol. 17(20), pages 1-12, October.
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