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An Update on the Implications of New Psychoactive Substances in Public Health

Author

Listed:
  • Ana Y. Simão

    (Centro de Investigação em Ciências da Saúde (CICS-UBI), Universidade da Beira Interior, 6200-506 Covilha, Portugal
    Laboratório de Fármaco-Toxicologia, UBIMedical, Universidade da Beira Interior, 6200-284 Covilha, Portugal)

  • Mónica Antunes

    (Centro de Investigação em Ciências da Saúde (CICS-UBI), Universidade da Beira Interior, 6200-506 Covilha, Portugal
    Serviço de Química e Toxicologia Forenses, Instituto Nacional de Medicina Legal e Ciências Forenses, Delegação do Sul, 1150-219 Lisboa, Portugal)

  • Emanuel Cabral

    (Centro de Investigação em Ciências da Saúde (CICS-UBI), Universidade da Beira Interior, 6200-506 Covilha, Portugal
    These authors contributed equally to this work.)

  • Patrik Oliveira

    (Centro de Investigação em Ciências da Saúde (CICS-UBI), Universidade da Beira Interior, 6200-506 Covilha, Portugal
    These authors contributed equally to this work.)

  • Luana M. Rosendo

    (Centro de Investigação em Ciências da Saúde (CICS-UBI), Universidade da Beira Interior, 6200-506 Covilha, Portugal
    These authors contributed equally to this work.)

  • Ana Teresa Brinca

    (Centro de Investigação em Ciências da Saúde (CICS-UBI), Universidade da Beira Interior, 6200-506 Covilha, Portugal
    These authors contributed equally to this work.)

  • Estefânia Alves

    (Centro de Investigação em Ciências da Saúde (CICS-UBI), Universidade da Beira Interior, 6200-506 Covilha, Portugal
    These authors contributed equally to this work.)

  • Hernâni Marques

    (Centro de Investigação em Ciências da Saúde (CICS-UBI), Universidade da Beira Interior, 6200-506 Covilha, Portugal
    Laboratório de Fármaco-Toxicologia, UBIMedical, Universidade da Beira Interior, 6200-284 Covilha, Portugal
    These authors contributed equally to this work.)

  • Tiago Rosado

    (Centro de Investigação em Ciências da Saúde (CICS-UBI), Universidade da Beira Interior, 6200-506 Covilha, Portugal
    Laboratório de Fármaco-Toxicologia, UBIMedical, Universidade da Beira Interior, 6200-284 Covilha, Portugal)

  • Luís A. Passarinha

    (Centro de Investigação em Ciências da Saúde (CICS-UBI), Universidade da Beira Interior, 6200-506 Covilha, Portugal
    UCIBIO—Applied Molecular Biosciences Unit, Departamento de Química, NOVA School of Science and Technology, Universidade NOVA, 2829-516 Caparica, Portugal
    Associate Laboratory i4HB-Institute for Health and Bioeconomy, NOVA School of Science and Technology, Universidade NOVA, 2819-516 Caparica, Portugal)

  • Maristela Andraus

    (Chromatox/Dasa Laboratory Ltda. Sumaré, São Paulo 01259-000, Brazil)

  • Mário Barroso

    (Serviço de Química e Toxicologia Forenses, Instituto Nacional de Medicina Legal e Ciências Forenses, Delegação do Sul, 1150-219 Lisboa, Portugal)

  • Eugenia Gallardo

    (Centro de Investigação em Ciências da Saúde (CICS-UBI), Universidade da Beira Interior, 6200-506 Covilha, Portugal
    Laboratório de Fármaco-Toxicologia, UBIMedical, Universidade da Beira Interior, 6200-284 Covilha, Portugal)

Abstract

The emergence of new psychoactive substances has earned a great deal of attention, and several reports of acute poisoning and deaths have been issued involving, for instance, synthetic opiates. In recent years, there have been profound alterations in the legislation concerning consumption, marketing, and synthesis of these compounds; rapid alert systems have also been subject to changes, and new substances and new markets, mainly through the internet, have appeared. Their effects and how they originate in consumers are still mostly unknown, primarily in what concerns chronic toxicity. This review intends to provide a detailed description of these substances from the point of view of consumption, toxicokinetics, and health consequences, including case reports on intoxications in order to help researchers and public health agents working daily in this area.

Suggested Citation

  • Ana Y. Simão & Mónica Antunes & Emanuel Cabral & Patrik Oliveira & Luana M. Rosendo & Ana Teresa Brinca & Estefânia Alves & Hernâni Marques & Tiago Rosado & Luís A. Passarinha & Maristela Andraus & Má, 2022. "An Update on the Implications of New Psychoactive Substances in Public Health," IJERPH, MDPI, vol. 19(8), pages 1-42, April.
    • Handle: RePEc:gam:jijerp:v:19:y:2022:i:8:p:4869-:d:795668
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    References listed on IDEAS

    as
    1. Maria Rosaria Varì & Giulio Mannocchi & Roberta Tittarelli & Laura Leondina Campanozzi & Giulio Nittari & Alessandro Feola & Federica Umani Ronchi & Giovanna Ricci, 2020. "New Psychoactive Substances: Evolution in the Exchange of Information and Innovative Legal Responses in the European Union," IJERPH, MDPI, vol. 17(22), pages 1-15, November.
    2. Barbara Lovrecic & Mercedes Lovrecic & Branko Gabrovec & Marco Carli & Matteo Pacini & Angelo G. I. Maremmani & Icro Maremmani, 2019. "Non-Medical Use of Novel Synthetic Opioids: A New Challenge to Public Health," IJERPH, MDPI, vol. 16(2), pages 1-21, January.
    Full references (including those not matched with items on IDEAS)

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