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The Influence of Research Follow-Up during COVID-19 Pandemic on Mental Distress and Resilience: A Multicenter Cohort Study of Treatment-Resistant Depression

Author

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  • Pham Thi Thu Huong

    (School of Nursing, National Taiwan University College of Medicine, Taipei 10051, Taiwan
    Faculty of Nursing and Midwifery, Hanoi Medical University, Hanoi 116177, Vietnam
    National Institute of Mental Health, Bach Mai Hospital, Hanoi 116300, Vietnam)

  • Chia-Yi Wu

    (School of Nursing, National Taiwan University College of Medicine, Taipei 10051, Taiwan
    Department of Nursing, National Taiwan University Hospital, Taipei 10051, Taiwan
    Taiwan Suicide Prevention Center, Taiwanese Society of Suicidology, Taipei 10051, Taiwan)

  • Ming-Been Lee

    (Taiwan Suicide Prevention Center, Taiwanese Society of Suicidology, Taipei 10051, Taiwan
    Department of Psychiatry, Shin Kong Wu Ho-Su Memorial Hospital, Taipei 11101, Taiwan
    Department of Psychiatry, National Taiwan University Hospital, Taipei 10051, Taiwan)

  • Wei-Chieh Hung

    (School of Nursing, National Taiwan University College of Medicine, Taipei 10051, Taiwan
    Department of Nursing, Far Eastern Memorial Hospital, New Taipei City 220, Taiwan)

  • I-Ming Chen

    (Department of Psychiatry, National Taiwan University Hospital, Taipei 10051, Taiwan)

  • Hsi-Chung Chen

    (Department of Psychiatry, National Taiwan University Hospital, Taipei 10051, Taiwan
    Center of Sleep Disorders, National Taiwan University Hospital, Taipei 10051, Taiwan)

Abstract

Background: During the COVID-19 outbreak, patients with mental disorders have faced more negative psychological consequences than the public. For people with treatment-resistant depression (TRD), it is unclear whether research engagement would protect them from the deterioration of their symptoms. The study aimed to examine if chronic depressive patients would have improved resilience and mental distress levels after follow-up interviews during an observation period under COVID-19. Methods: The study was nested within a three-year prospective cohort study. A two-group comparison design was conducted, i.e., the follow-up group with regular research interviews every three months after baseline assessment and the control group with one assessment-only interview. The two groups were compared with demographics, psychosocial, and suicide information. Results: Baseline assessments were not significantly different in sociodemographic variables, suicide risks, mental distress, and resilience between groups. Significant differences were detected in resilient coping and mental distress levels ( p < 0.05). The follow-up group ( n = 46) experienced a higher level of resilient coping (37% vs. 25%) and lower level of mental distress (47.8% vs. 64.7%) than the control group ( n = 68). Conclusions: Findings highlight under universal government strategy against COVID-19, TRD patients receiving regular research follow-ups exhibited better resilience and less mental distress than those without regular support from healthcare providers.

Suggested Citation

  • Pham Thi Thu Huong & Chia-Yi Wu & Ming-Been Lee & Wei-Chieh Hung & I-Ming Chen & Hsi-Chung Chen, 2022. "The Influence of Research Follow-Up during COVID-19 Pandemic on Mental Distress and Resilience: A Multicenter Cohort Study of Treatment-Resistant Depression," IJERPH, MDPI, vol. 19(6), pages 1-11, March.
    • Handle: RePEc:gam:jijerp:v:19:y:2022:i:6:p:3738-:d:776149
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    References listed on IDEAS

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    1. Orhan Koçak & Ömer Erdem Koçak & Mustafa Z. Younis, 2021. "The Psychological Consequences of COVID-19 Fear and the Moderator Effects of Individuals’ Underlying Illness and Witnessing Infected Friends and Family," IJERPH, MDPI, vol. 18(4), pages 1-15, February.
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