IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v19y2022i5p3094-d765229.html
   My bibliography  Save this article

The Risk of Herpes Zoster in Women with Polycystic Ovary Syndrome: A Retrospective Population-Based Study

Author

Listed:
  • Wen-Che Hsieh

    (Department of Chinese Medicine, Ditmanson Medical Foundation, Chia-Yi Christian Hospital, Chia-Yi 600, Taiwan)

  • Chia-Hung Chen

    (Department of Medical Education, Ditmanson Medical Foundation, Chia-Yi Christian Hospital, Chia-Yi 600, Taiwan
    Department of Medical Imaging, Ditmanson Medical Foundation, Chia-Yi Christian Hospital, Chia-Yi 600, Taiwan)

  • Yung-Chi Cheng

    (Department of Medical Education, Ditmanson Medical Foundation, Chia-Yi Christian Hospital, Chia-Yi 600, Taiwan
    Department of Rehabilitation, Ditmanson Medical Foundation Chia-Yi Christian Hospital, Chia-Yi 600, Taiwan)

  • Teng-Shun Yu

    (Management Office for Health Data, China Medical University Hospital, Taichung 404, Taiwan
    College of Medicine, China Medical University, Taichung 404, Taiwan)

  • Chung Y. Hsu

    (Graduate Institute of Biomedical Sciences, China Medical University, Taichung 404, Taiwan)

  • Der-Shin Ke

    (Department of Neurology, Ditmanson Medical Foundation, Chia-Yi Christian Hospital, Chia-Yi 600, Taiwan)

  • Chih-Ming Lin

    (Department of Laboratory Medicine, Ditmanson Medical Foundation, Chia-Yi Christian Hospital, Chia-Yi 600, Taiwan
    These authors contributed equally to this work.)

  • Chao-Yu Hsu

    (Department of Medical Education, Ditmanson Medical Foundation, Chia-Yi Christian Hospital, Chia-Yi 600, Taiwan
    Department of Optometry/Medical Imaging and Radiological Sciences, Central Taiwan University of Science and Technology, Taichung 406, Taiwan
    Center for General Education, National Taichung University of Science and Technology, Taichung 404, Taiwan
    Department of General Education, National Chin-Yi University of Technology, Taichung 411, Taiwan)

Abstract

Background: The association between polycystic ovary syndrome (PCOS) and the risk of herpes zoster (HZ) remains unclear. This study investigated the risk of HZ in women with PCOS. Methods: This study used data from the Longitudinal Generation Tracking Database (LGTD 2005) which contains the information of 2 million randomly selected from National Health Insurance beneficiaries. Patients who received a diagnosis of PCOS between 2000 and 2017 were included in the PCOS cohort. Patients who were not diagnosed as having PCOS were randomly selected from the LGTD 2005 and included in the control cohort. Patients who were aged <20 years and had a history of HZ before the index date were excluded. Patients who were in both the cohorts were matched at a ratio of 1:1 through propensity score matching based on age, comorbidities, and medication. The primary outcome was the diagnosis of HZ. Results: A total of 20,142 patients were included in each case and control cohorts. The incidence rates of HZ in the PCOS and control cohorts were 3.92 and 3.17 per 1000 person-years, respectively. The PCOS cohort had a significantly higher risk of HZ than did the control cohort (adjusted hazard ratios [aHR] = 1.26). Among the patients aged 30–39 years, those with PCOS had a significantly higher risk of HZ than did those without PCOS (aHR = 1.31). Among the patients without any comorbidities, those with PCOS had a significantly higher risk of HZ (aHR = 1.26) than did those without PCOS. Conclusion: PCOS is associated with the risk of HZ, especially in young women. The risk of HZ should be addressed while treating patients with PCOS. An HZ vaccine is recommended for these patients.

Suggested Citation

  • Wen-Che Hsieh & Chia-Hung Chen & Yung-Chi Cheng & Teng-Shun Yu & Chung Y. Hsu & Der-Shin Ke & Chih-Ming Lin & Chao-Yu Hsu, 2022. "The Risk of Herpes Zoster in Women with Polycystic Ovary Syndrome: A Retrospective Population-Based Study," IJERPH, MDPI, vol. 19(5), pages 1-8, March.
    • Handle: RePEc:gam:jijerp:v:19:y:2022:i:5:p:3094-:d:765229
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/19/5/3094/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/19/5/3094/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Chao-Yu Hsu & Der-Shin Ke & Cheng-Li Lin & Chia-Hung Kao, 2020. "Risk of Herpes Zoster in Patients with Adhesive Capsulitis of the Shoulder," IJERPH, MDPI, vol. 17(10), pages 1-8, May.
    2. Chao-Yu Hsu & Cheng-Li Lin & Chia-Hung Kao, 2020. "Association between Chronic Interstitial Cystitis and Herpes Zoster," IJERPH, MDPI, vol. 17(7), pages 1-8, March.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Chao-Yu Hsu & Der-Shin Ke & Cheng-Li Lin & Chia-Hung Kao, 2020. "Risk of Herpes Zoster in Patients with Adhesive Capsulitis of the Shoulder," IJERPH, MDPI, vol. 17(10), pages 1-8, May.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:19:y:2022:i:5:p:3094-:d:765229. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.