Author
Listed:
- Sophia C. Mylonakis
(Infectious Diseases Division, Warren Alpert Medical School of Brown University, Providence, RI 02903, USA)
- Evangelia K. Mylona
(Infectious Diseases Division, Warren Alpert Medical School of Brown University, Providence, RI 02903, USA)
- Markos Kalligeros
(Infectious Diseases Division, Warren Alpert Medical School of Brown University, Providence, RI 02903, USA
Department of Medicine, Warren Alpert Medical School of Brown University, Providence, RI 02903, USA)
- Fadi Shehadeh
(Infectious Diseases Division, Warren Alpert Medical School of Brown University, Providence, RI 02903, USA
School of Electrical and Computer Engineering, National Technical University of Athens, 15780 Athens, Greece)
- Philip A. Chan
(Infectious Diseases Division, Warren Alpert Medical School of Brown University, Providence, RI 02903, USA
Division of Preparedness, Response, Infectious Disease, and Emergency Medical Services, Rhode Island Department of Health, Providence, RI 02908, USA)
- Eleftherios Mylonakis
(Infectious Diseases Division, Warren Alpert Medical School of Brown University, Providence, RI 02903, USA)
Abstract
Influenza is a contagious respiratory illness and can lead to hospitalization and even death. Understanding how comorbidities affect the severity of influenza can help clinical management. The aim of this study is to offer more information about comorbidities that might be associated with the severity of influenza in children. We used a statewide network in Rhode Island, USA, to extract data for laboratory-confirmed influenza cases among children 19 years old or younger. We identified 1169 lab-confirmed influenza cases. The most common comorbidities were asthma (17.1%), neurodevelopmental disorders (10.3%), gastrointestinal disorders (7.6%), atopic dermatitis (7%), and endocrine and metabolic diseases (6.8%). Interestingly, 80.8% (63 out of 78) of children who had an influenza-related hospital admission had at least one comorbidity, and among hospitalized children with influenza, the most common comorbidities were neurological diseases (28.2%, 22/78), gastrointestinal disorders (25.6%, 20/78), endocrine and metabolic diseases (24.4%, 19/78), and neurodevelopmental disorders (23.1%, 18/78). Children with endocrine or metabolic diseases were 8.23 times more likely to be admitted to the hospital, and children with neurological disorders were 6.35 times more likely to be admitted (OR: 8.23, 95% CI: 4.42–15.32 and OR: 6.35, 95% CI: 3.60–11.24, respectively). In summary, we identified specific comorbidities associated with influenza hospitalization and length of hospital stay, and these groups should be prioritized for public health interventions.
Suggested Citation
Sophia C. Mylonakis & Evangelia K. Mylona & Markos Kalligeros & Fadi Shehadeh & Philip A. Chan & Eleftherios Mylonakis, 2022.
"How Comorbidities Affect Hospitalization from Influenza in the Pediatric Population,"
IJERPH, MDPI, vol. 19(5), pages 1-9, February.
Handle:
RePEc:gam:jijerp:v:19:y:2022:i:5:p:2811-:d:760516
Download full text from publisher
Corrections
All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:19:y:2022:i:5:p:2811-:d:760516. See general information about how to correct material in RePEc.
If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.
We have no bibliographic references for this item. You can help adding them by using this form .
If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.
For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .
Please note that corrections may take a couple of weeks to filter through
the various RePEc services.