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A Systematic Review of Recreational Nitrous Oxide Use: Implications for Policy, Service Delivery and Individuals

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  • Julaine Allan

    (School of Health and Society, University of Wollongong, Wollongong, NSW 2522, Australia
    Rural Health Research Institute, Charles Sturt University, Orange, NSW 2800, Australia)

  • Jacqui Cameron

    (School of Health and Society, University of Wollongong, Wollongong, NSW 2522, Australia
    Department of Social Work, The University of Melbourne, Parkville, VIC 3010, Australia)

  • Juliana Bruno

    (School of Health and Society, University of Wollongong, Wollongong, NSW 2522, Australia)

Abstract

Background: Nitrous oxide (N 2 O) is a dissociative anaesthetic that is sometimes used recreationally. The prevalence of N 2 O use is difficult to quantify but appears to be increasing. Research on N 2 O harms and application of harm reduction strategies are limited. The aim of this mixed method systematic review was to collate and synthesise the disparate body of research on recreational nitrous oxide use to inform harm reduction approaches tailored for young people. Methods: To identify publications reporting the recreational use of N 2 O, a search of public health, psychology and social science databases was conducted. Databases included PubMed, CIHNAL, PsycINFO, Scopus and Web of Science . Grey literature and Google advanced search were also used. Due to limited published literature on the recreational use of N 2 O, no limit was placed on publication date or study type. A thematic synthesis extracted descriptive and analytical themes from the selected studies. Quality appraisal was conducted using the CASP Tool for Qualitative studies and the Joanna Briggs Institute case report assessment tool. Results: The search retrieved 407 reports. Thirty-four were included in the final analysis, including sixteen case reports. The included studies were primarily concerned with raising awareness of the apparently increasing use and subsequently increasing harms of recreational N 2 O use. There was limited reference to policy or legislative responses in any published studies, no suggestions for harm reduction strategies or application of service level responses. In general, individuals lack awareness of N 2 O-related harms. Conclusion: The review found three key areas that deserve further consideration including: (1) policy, (2) service delivery, and (3) harm associated with N 2 O use. We recommend a top–down (policy) and bottom–up (services delivery/services users) approach to harm reduction for N 2 O use which also includes further consultation and research with both groups. Future research could explore young people’s experience of N 2 O use including benefits and problems to inform contextually relevant harm reduction strategies.

Suggested Citation

  • Julaine Allan & Jacqui Cameron & Juliana Bruno, 2022. "A Systematic Review of Recreational Nitrous Oxide Use: Implications for Policy, Service Delivery and Individuals," IJERPH, MDPI, vol. 19(18), pages 1-18, September.
    • Handle: RePEc:gam:jijerp:v:19:y:2022:i:18:p:11567-:d:914730
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    References listed on IDEAS

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    1. Suzanne J van den Toren & Amy van Grieken & Hein Raat, 2021. "Associations of socio-demographic characteristics, well-being, school absenteeism, and substance use with recreational nitrous oxide use among adolescents: A cross-sectional study," PLOS ONE, Public Library of Science, vol. 16(2), pages 1-14, February.
    2. Ton Nabben & Jelmer Weijs & Jan van Amsterdam, 2021. "Problematic Use of Nitrous Oxide by Young Moroccan–Dutch Adults," IJERPH, MDPI, vol. 18(11), pages 1-17, May.
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    1. Ton Nabben & Jelmer Weijs & Jan van Amsterdam, 2021. "Problematic Use of Nitrous Oxide by Young Moroccan–Dutch Adults," IJERPH, MDPI, vol. 18(11), pages 1-17, May.

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