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Gout as a Risk Factor for Age-Related Macular Degeneration in Taiwanese Adults—A Population-Based Study in Taiwan

Author

Listed:
  • Min-Huei Hsu

    (Graduate Institute of Data Science, College of Management, Taipei Medical University, Taipei 11042, Taiwan
    Department of Neurosurgery, Shuang Ho Hospital, Taipei Medical University, Taipei 23561, Taiwan)

  • Chia-An Hsu

    (Department of Ophthalmology, Taipei Veterans General Hospital, Taipei 11217, Taiwan)

  • Shih-Chung Lai

    (Department of Ophthalmology, Shuang Ho Hospital, Taipei Medical University, Taipei 23561, Taiwan)

  • Ju-Chuan Yen

    (Graduate Institute of Biomedical Informatics, College of Medical Science and Technology, Taipei Medical University, Taipei 11042, Taiwan
    Department of Ophthalmology, Ren-Ai Branch, Taipei City Hospital, Taipei 10341, Taiwan
    Department of Education and Research, Taipei City Hospital, Taipei 10341, Taiwan
    University of Taipei, Taipei 10048, Taiwan)

Abstract

The relationship between gout and age-related macular degeneration (AMD) was suggested in previous literature but has yet to be accepted fully among physicians. This study aimed to explore the effect of gout on the development of age-related macular degeneration in Taiwan. A retrospective cohort study was conducted using Taiwan’s National Health Insurance Database that includes a 2-million-persons dataset. The crude hazard ratio, Kaplan–Meier plot, and separate cox proportional hazard ratio were utilized to demonstrate the effect of gout on the development of age-related macular degeneration. The crude hazard ratio for gout patients developing AMD was 1.55 and the adjusted hazard ratio 1.20. In conclusion, gout is a risk factor for developing AMD, and achieving good disease management is therefore essential for preventing AMD from occurring.

Suggested Citation

  • Min-Huei Hsu & Chia-An Hsu & Shih-Chung Lai & Ju-Chuan Yen, 2022. "Gout as a Risk Factor for Age-Related Macular Degeneration in Taiwanese Adults—A Population-Based Study in Taiwan," IJERPH, MDPI, vol. 19(16), pages 1-9, August.
    • Handle: RePEc:gam:jijerp:v:19:y:2022:i:16:p:10142-:d:889548
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    References listed on IDEAS

    as
    1. Jasvinder A Singh & John D Cleveland, 2018. "Gout and the risk of age-related macular degeneration in the elderly," PLOS ONE, Public Library of Science, vol. 13(7), pages 1-14, July.
    2. Ju-Chuan Yen & Chia-An Hsu & Sheng-Huang Hsiao & Min-Huei Hsu, 2017. "Acute Anterior Uveitis as a Risk Factor of Ankylosing Spondylitis—A National Population-Based Study," IJERPH, MDPI, vol. 14(1), pages 1-7, January.
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